Rhinocerebral Mucormycosis Presented with Cranial Nerves Deficit | ||||
| Afro-Egyptian Journal of Infectious and Endemic Diseases | ||||
| Article 9, Volume 5, Issue 3, September 2015, Page 201-204 PDF (139.13 K) | ||||
| Document Type: Case report | ||||
| DOI: 10.21608/aeji.2015.17831 | ||||
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| Authors | ||||
| Maysaa Abdallah Saeed1; Tarek H Attia2; Abdullah S Al Ghamdi3 | ||||
| 1Tropical Medicine Department, Faculty of Medicine, Zagazig University, Egypt. | ||||
| 2Pediatric Department, Faculty of Medicine, Zagazig University, Egypt. | ||||
| 3Internal Medicine Department, King Saud Medical City, Kingdom of Saudi Arabia. | ||||
| Abstract | ||||
| Mucormycosis is a rare opportunistic fungal infection, associated with high mortality, characterized by infarction and necrosis of host tissue. Rhinocerebral mucormycosis (RCM) is the most common clinical variant often associated with poorly controlled diabetes mellitus. The treatment is complex and involves both antifungal and surgery. There is no formal guideline regarding the duration of antifungal, timing and extent of surgical management. We present a case of RCM in a diabetic girl who presented with a 2 weeks history of left facial and periorbital swelling associated with left facial numbness and deficit of the fifth and seventh cranial nerves. Diagnosis of RCM was confirmed by histopathological examination of tissue biopsy. She was successfully treated with liposomal amphotericin B and posaconazole, as step-down therapy, along with minimal surgical debridement. We present this case because of the rarity of RCM, calling for prompt initiation of treatment in a suspected case and to present data about therapeutic modality. | ||||
| Keywords | ||||
| Diabetes mellitus; mucormycosis; zygomycosis | ||||
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