Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C | ||||
| Afro-Egyptian Journal of Infectious and Endemic Diseases | ||||
| Article 4, Volume 5, Issue 4, December 2015, Page 235-245 PDF (357.18 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/aeji.2015.17844 | ||||
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| Authors | ||||
| Mohammed A Nouh1; Hatem M El Sebaey2; Somaia A Shehab El-Deen1; Sherif AA Allam3 | ||||
| 1Tropical Medicine Department, Faculty of Medicine, Menoufia University, Egypt. | ||||
| 2Medical Biochemistry Department, Faculty of Medicine, Menoufia University, Egypt. | ||||
| 3Tanta Fever Hospital , Tanta ,Egypt. | ||||
| Abstract | ||||
| Background and study aim : Monitoring of liver fibrosis progression is important in patients with chronic hepatitis C .The aim of this study is to verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C compared with other noninvasive tests. Patients and methods: This study included 90 naïve patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treatment and 20 healthy volunteers as a control group. FibroQ, aspartate aminotransferase (AST)/alanine amino-transferase ratio (AAR), AST to platelet ratio index, cirrhosis discriminates score, age-platelet index (API), Pohl score, FIB-4 index, and Lok’s model were calculated and compared. Results: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced .FibroQ trended to be superior in predicting significant fibrosis score in chronic hepatitis C compared with other noninvasive tests. Conclusion: FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C. | ||||
| Keywords | ||||
| Liver fibrosis; FibroQ; FIB-4 index; Lok’s model; Cirrhosis discriminant score; Pohl score | ||||
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