Septic Shock in Pediatrics | ||||
Afro-Egyptian Journal of Infectious and Endemic Diseases | ||||
Article 13, Volume 5, Issue 4, December 2015, Page 311-316 PDF (276.83 K) | ||||
Document Type: Review article and meta analysis | ||||
DOI: 10.21608/aeji.2015.17853 | ||||
View on SCiNiTO | ||||
Authors | ||||
Tarek Hamed Attia 1; Maysaa Abdallah Saeed2 | ||||
1Pediatric Department, Faculty of Medicine, Zagazig University, Egypt | ||||
2Tropical Medicine Department, Faculty of Medicine, Zagazig University, Egypt | ||||
Abstract | ||||
Sepsis is defined as a clinical syndrome that complicates severe infection and is associated with the systemic inflammatory response syndrome as well as immune dysregulation. Circulatory decompensation and end-organ dysfunction will be the ultimate end if sepsis is not properly managed. In this syndrome, tissues remote from the original insult display the cardinal signs of inflammation, including vasodilation, increased microvascular permeability and leukocyte accumulation. Recently pediatric mortality from severe sepsis and septic shock has markedly decreased because of early recognition, aggressive fluid therapy and early administration of vasoactive agents in addition to antibiotics. | ||||
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