Using Microwave and ultrasound to prepare of substituted Bis-acyl hydrazone Derivatives
Mohammed, S., Sheat, A., Abood, S., Yahya, O. (2021). Using Microwave and ultrasound to prepare of substituted Bis-acyl hydrazone Derivatives. EKB Journal Management System, 64(11), 6423-6427. doi: 10.21608/ejchem.2021.78532.3842
Salim J. Mohammed; Attallah M. Sheat; Salih A. Abood; Omar M. Yahya. "Using Microwave and ultrasound to prepare of substituted Bis-acyl hydrazone Derivatives". EKB Journal Management System, 64, 11, 2021, 6423-6427. doi: 10.21608/ejchem.2021.78532.3842
Mohammed, S., Sheat, A., Abood, S., Yahya, O. (2021). 'Using Microwave and ultrasound to prepare of substituted Bis-acyl hydrazone Derivatives', EKB Journal Management System, 64(11), pp. 6423-6427. doi: 10.21608/ejchem.2021.78532.3842
Mohammed, S., Sheat, A., Abood, S., Yahya, O. Using Microwave and ultrasound to prepare of substituted Bis-acyl hydrazone Derivatives. EKB Journal Management System, 2021; 64(11): 6423-6427. doi: 10.21608/ejchem.2021.78532.3842

Using Microwave and ultrasound to prepare of substituted Bis-acyl hydrazone Derivatives

Egyptian Journal of Chemistry
Article 27, Volume 64, Issue 11, November 2021, Page 6423-6427  XML PDF (454.8 K)
Document Type: Original Article
DOI: 10.21608/ejchem.2021.78532.3842
View on SCiNiTO View on SCiNiTO
Authors
Salim J. Mohammed1; Attallah M. Sheat1; Salih A. Abood1; Omar M. Yahya2
1Department of Chemistry, College of Science, Mosul University, Mosul, Iraq
2Department of Biochemistry, College of Medicine, Mosul University, Mosul-Iraq
Abstract
Abstract
In this paper, some new bis-aryl hydrazone derivatives (4a-f) were prepared through the reaction of carboxylic acid hydrazides with 1,4-diacetylbenzene using classical methods, microwave and ultrasound irradiation methods. These compounds are obtained through a series of reactions where some carboxylic acids react with ethanol first in the presence of concentrated sulfuric acid to give the corresponding esters (2a-f), which when treatment with aqueous hydrazine give carboxylic acid hydrazides (3a-f).thus, The results proved that the use of microwave and ultrasound techniques is much better than the classical methods, as it gave a higher yield, shorter reaction time, and the absence of the use of solvents. All newly synthesized compounds were confirmed by IR, (1H & 13C) NMR spectral analysis and the corresponding reactions were
monitored by TLC using the reported eluent
Keywords
Keywoords: bis-acyl hydrazone; acid hydrazide; 1; 4-diacetylbenzene; Microwave; ultrasound technique
Statistics
Article View: 467
PDF Download: 259