HOMOISOFLAVANONES FROM SCILLA (LILIACEAE) | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 4, Volume 11, Issue 2, December 2002, Page 29-33 PDF (2.19 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.2002.178958 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mona Zaghloul ; Hosny Abd El-Fattah; Ahmed Zaghloul | ||||
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. | ||||
Abstract | ||||
Phytochemical investigation of the ether fraction of the methanolic extract of Scilla peruviana, S. villosa and S.numedica, led to the isolation of three homoisoflavanones 1, 2, and 3. They were identified according to their chemical and spectral data as 5,7-dihydroxy-6-methoxy-3-(4-methoxybenzyl) chroman-4-one, 5,7-dihydroxy-6- methoxy-3-(4-hydroxybenzyl) chroman-4-one, and 5,7-dihydroxy-6-methoxy-3-(4-hydroxy benzylidene) chroman-4-one (autumnalin) respectively The isolated compounds showed anti-bacterial activity against Gram positive and Gram negative bacteria as well as anti-fungal activity. In addition, the ether extracts of S. peruviana and S. villosa showed anti-inflammatory activity. | ||||
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