Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species
Areida, S., Ismail, M., Abdel Hady, E., Osman, A. (2006). Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species. EKB Journal Management System, 23(1), 287-308. doi: 10.21608/ejhm.2006.17941
S. K. Areida; M. F. Ismail; E. K. Abdel Hady; A. O. Osman. "Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species". EKB Journal Management System, 23, 1, 2006, 287-308. doi: 10.21608/ejhm.2006.17941
Areida, S., Ismail, M., Abdel Hady, E., Osman, A. (2006). 'Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species', EKB Journal Management System, 23(1), pp. 287-308. doi: 10.21608/ejhm.2006.17941
Areida, S., Ismail, M., Abdel Hady, E., Osman, A. Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species. EKB Journal Management System, 2006; 23(1): 287-308. doi: 10.21608/ejhm.2006.17941

Molecular Characterization Of Hair Cuticle And Its Extracted Proteins In Seven Mammalian Species

The Egyptian Journal of Hospital Medicine
Article 11, Volume 23, Issue 1, April 2006, Page 287-308  XML PDF (1.54 MB)
Document Type: Original Article
DOI: 10.21608/ejhm.2006.17941
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Authors
S. K. Areida; M. F. Ismail; E. K. Abdel Hady; A. O. Osman
Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Abstract
Hairisanoftheepidermisinmammalsandconsistsoftwolargegroupsofhumanhair proteins.Oneishardα-keratinsandtheotherismatrixproteins.Thepresentinvestigationaimed tocomparetheultrastructuralofthehairscaleusingthescanningelectronmicroscope,andthe proteinsandaminoacidscontentofthekeratininsevenmammalianspecies.
Thevaluesofthehairthickness,x/yferetandhairpatternofthespeciesinthepresent studyconfirmthepresenceofspecies-specificcharacteristicsandultrastructuralvariation.The situationinmandiffersfromthewildmammalsduetodamageofhaircuticlecausedby mechanicalabuse,exposuretoultravioletradiationandchemicaloverprocessing.The maximumamountofextractedproteinsfromhairkeratinwasanalyzedbySDS-PAGE.The electrophoreticpatternsshowedanoveralldegreeofsimilarity.However,differencesexist betweenspeciesintheintensityofstain.Quantitatively,theelectrophoreticpatternsscannedand analyzedusinggelproteinanalyzer.Theresultsshowednodifferencebetweenthemolecular massofsomespecies,butdifferentinmolecularmassdistribution.
Aminoacidcompositionofkeratinofmammalianhairspeciesofthepresentstudy showedsomevariation,especiallyformethionine,isoleucine,lysineandarginine.Theother aminoacidsstudiedaresignificantlypresentinmosthair.Oneofthelateraminoacidis




cysteine.Cysteineisaveryimportantdueto hepresenceofdisulfatecross-links.
 
 
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