COVID-19 Infection and Early Outcome of Acute Peripheral Vascular Events A propensity Score Matching Analysis
Tawfik, A., tawfeek, H., Elboushi, A., Elsabbagh, M., Salem, A., Zidan, M. (2022). COVID-19 Infection and Early Outcome of Acute Peripheral Vascular Events A propensity Score Matching Analysis. EKB Journal Management System, 28(4), 784-790. doi: 10.21608/zumj.2021.74555.2217
Ahmed Tawfik; hossam ahmed tawfeek; Amro Elboushi; Mahmoud Ahmed Elsabbagh; Ayman Salem; Mohamed Hamed Zidan. "COVID-19 Infection and Early Outcome of Acute Peripheral Vascular Events A propensity Score Matching Analysis". EKB Journal Management System, 28, 4, 2022, 784-790. doi: 10.21608/zumj.2021.74555.2217
Tawfik, A., tawfeek, H., Elboushi, A., Elsabbagh, M., Salem, A., Zidan, M. (2022). 'COVID-19 Infection and Early Outcome of Acute Peripheral Vascular Events A propensity Score Matching Analysis', EKB Journal Management System, 28(4), pp. 784-790. doi: 10.21608/zumj.2021.74555.2217
Tawfik, A., tawfeek, H., Elboushi, A., Elsabbagh, M., Salem, A., Zidan, M. COVID-19 Infection and Early Outcome of Acute Peripheral Vascular Events A propensity Score Matching Analysis. EKB Journal Management System, 2022; 28(4): 784-790. doi: 10.21608/zumj.2021.74555.2217

COVID-19 Infection and Early Outcome of Acute Peripheral Vascular Events A propensity Score Matching Analysis

Zagazig University Medical Journal
Article 22, Volume 28, Issue 4, July 2022, Page 784-790  XML PDF (260.88 K)
Document Type: Original Article
DOI: 10.21608/zumj.2021.74555.2217
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Authors
Ahmed Tawfikorcid 1; hossam ahmed tawfeek2; Amro Elboushi3; Mahmoud Ahmed Elsabbagh4; Ayman Salem5; Mohamed Hamed Zidan email orcid 5
1Vascular surgery
2Faculty of Medicine, Zagazig University, Department of Vascular Surgery, Sharkia Egypt
3Vascular surgery department, faculty of medicine, zagazig university Department of Vascular , University Hospitals Birmingham, United Kingdom
4Vascular surgery department, faculty of medicine, zagazig university,
5Vascular surgery department, faculty of medicine, zagazig university
Abstract
Abstract
Background and aim: The present study aimed to compare the short term outcome of thromboembolic events affecting the peripheral vascular system in patients with concomitant COVID-19 infection and patients without this infection.
Patients and methods: The study included 177 covid-19 patients with peripheral vascular events. They comprised 62 patients with acute lower limb ischemia, 69 patients with lower limb DVT, 21 patients with thrombosed vascular access and 25 patients with occluded lower limb bypass graft. For comparison, we selected another 177 patients with peripheral vascular events without covid-19 infection. Patients were selected using a propensity score matching with 1:1 ratio. Patients were followed for 30 days after admission.
Results: Comparison between acute lower limb ischemia with and without covid-19 revealed that covid-19 patients had higher amputation rate (25.8 % versus 12.9 %, p=0.069) without statistical significance. However, multivariate regression analysis identified covid-19 infection as a significant predictor of limb amputation [OR (95% CI: 3.31 (1.15-9.6), p=0.027]. In DVT patients, covid-19 patients had significantly lower clinical improvement (75.4 % versus 91.3 %, p=0.012). In patients with vascular access thrombosis, covid-19 patients had lower secondary patency rates (61.9 % versus 71.4 %, p=0.52) without statistical significance. In patients with occluded lower limb bypass graft, covid-19 patients had markedly lower secondary patency rates despite falling short of statistical significance (68.0 % versus 88.0 %, p=0.088).
Conclusions: Covid-19 infection is related to worse outcome in many patients with peripheral vascular events particularly those with acute lower limb ischemia and DVT.
Keywords
Acute lower limb ischemia; deep venous thrombosis; vascular access; COVID-19
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