Possible relation between H. pylori and bilateral nasal polypi
Aref, Z., abdel Aziz, S., Fadel, S., Abdel Raheem, A., Abdelmaksoud, A. (2022). Possible relation between H. pylori and bilateral nasal polypi. EKB Journal Management System, 5(2), 348-354. doi: 10.21608/svuijm.2021.69625.1151
Zaki F. Aref; Shahenda Mostafa abdel Aziz; Sabah Ahmed Mohamed Fadel; Ahmed Gaber Abdel Raheem; Aida A. Abdelmaksoud. "Possible relation between H. pylori and bilateral nasal polypi". EKB Journal Management System, 5, 2, 2022, 348-354. doi: 10.21608/svuijm.2021.69625.1151
Aref, Z., abdel Aziz, S., Fadel, S., Abdel Raheem, A., Abdelmaksoud, A. (2022). 'Possible relation between H. pylori and bilateral nasal polypi', EKB Journal Management System, 5(2), pp. 348-354. doi: 10.21608/svuijm.2021.69625.1151
Aref, Z., abdel Aziz, S., Fadel, S., Abdel Raheem, A., Abdelmaksoud, A. Possible relation between H. pylori and bilateral nasal polypi. EKB Journal Management System, 2022; 5(2): 348-354. doi: 10.21608/svuijm.2021.69625.1151

Possible relation between H. pylori and bilateral nasal polypi

SVU-International Journal of Medical Sciences
Article 34, Volume 5, Issue 2, July 2022, Page 348-354  XML PDF (435.39 K)
Document Type: Original research articles
DOI: 10.21608/svuijm.2021.69625.1151
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Authors
Zaki F. Areforcid 1; Shahenda Mostafa abdel Aziz email 1; Sabah Ahmed Mohamed Fadel2; Ahmed Gaber Abdel Raheem1; Aida A. Abdelmaksoudorcid 1
1Department of Otorhinolaryngology. Faculty of Medicine, South Valley University, Qena, Egypt
2Department of Pathology, Faculty of Medicine, Assiut University, Qena, Egypt.
Abstract
Background: H.pylori is a Gram-negative bacterium known to be associated with peptic ulcer disease, gastric cancer, gastric lymphoma. Recently it was detected in mucosa of patients with CRS, but relation with bilateral nasal polyposis has not been demonstrated yet.
Objectives: H. pyloriis a pathogen that lives in the gastrointestinal tract (GIT) and has extragastric manifestations. Nasal polypi may be one of these manifestations. This study aims to detect the relation between H.pylori and bilateral nasal polypi.
 Patients and methods: This study includes 80 cases of nasal polypi, 40 of them were de novo bilateral nasal polypi and 40 were recurrent nasal polypi, biopsies of nasal polypi were taken under sterile conditions and stained with Giemsa stain and Hematoxylin and eosin(H&E) stain. Stool analysis was done to detect presence of H.pylori using rapid urease test.
Results: Both groups are age and sex matched. Nasal polyp biopsies showed positive results in 10 % of denovo group and 15 % of recurrent group with p value 0.449 which is not statistically significant. Stool antigen test showed positive results in 52.5 % of denovo group and 60 % of recurrent group with p value 0.449 which is not statistically significant.
Conclusion: There is no statistically significant relation between H.pylori and the pathogenesis of bilateral nasal polypi, further studies with large number of patients is recommended. 
Keywords
Bilateral Nasal polypi; H. pylori; Giemsa stain; Modified McMullen’s; Stool antigen test
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