Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis
Mohamed, N., El sayed, T. (2005). Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis. EKB Journal Management System, 21(1), 139-144. doi: 10.21608/ejhm.2005.18056
Nagwa Mohamed; Talaat El sayed. "Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis". EKB Journal Management System, 21, 1, 2005, 139-144. doi: 10.21608/ejhm.2005.18056
Mohamed, N., El sayed, T. (2005). 'Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis', EKB Journal Management System, 21(1), pp. 139-144. doi: 10.21608/ejhm.2005.18056
Mohamed, N., El sayed, T. Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis. EKB Journal Management System, 2005; 21(1): 139-144. doi: 10.21608/ejhm.2005.18056

Plasma Histamine And Serotonin Levels In Children With Nephrotic Syndrome And Acute Poststreptococcal Glomerulonephritis

The Egyptian Journal of Hospital Medicine
Article 12, Volume 21, Issue 1, October 2005, Page 139-144  XML PDF (200.94 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2005.18056
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Authors
Nagwa Mohamed1; Talaat El sayed2
1Child handicapped Center
2Faculty of Science AlAzhar University
Abstract
Plasma histamine and serotonin concentrations were measured using fluorimeteric assay in 40 children with renal diseases. Minimal change nephrotic syndrome (15) focal segmental glomerulosclerosis(10) and acute poststreptococcal glomerulonephritis(15) to determine the relation between plasma levels of histamine and serotonin and these various types of renal diseases in children. Plasma histamine level was significantly increased in group of children with acute poststreptococcal glomerulonephritis. Plasma serotonin levels were significantly increased in all 3 groups of patient, when compared with those of controls. Raised plasma histamine in acute poststreptococcal glomerulonephritis group may be evidence of the acute immunological inflammation and defective renal excretion due to mild renal impairment in these children. Raised plasma serotonin in all 3 groups of patients may be due to diminished uptake and release of serotonin from platelets in children with minimal change nephrotic syndrome and focal segmental glomerulosclerosis and due to defective renal execretion in children with acute poststreptococcal glomerulo-nephritis.
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