Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study)
Elwazir, A., Fahmy, O., Nabih, S. (2021). Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study). EKB Journal Management System, 1(1), 1-16. doi: 10.21608/jfcr.2021.181031
Amira Ahmed Elwazir; Ola Mohamed Fahmy; Sameh Mahmoud Nabih. "Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study)". EKB Journal Management System, 1, 1, 2021, 1-16. doi: 10.21608/jfcr.2021.181031
Elwazir, A., Fahmy, O., Nabih, S. (2021). 'Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study)', EKB Journal Management System, 1(1), pp. 1-16. doi: 10.21608/jfcr.2021.181031
Elwazir, A., Fahmy, O., Nabih, S. Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study). EKB Journal Management System, 2021; 1(1): 1-16. doi: 10.21608/jfcr.2021.181031

Effect of Sodium Hypochlorite (NaOCl) for Pretreatment of Early Demineralized Enamel Lesions in Enhancing the Remineralization Capacity of Self-assembling Peptide (In-vitro Study)

Journal of Fundamental and Clinical Research
Article 1, Volume 1, Issue 1, June 2021, Page 1-16  XML PDF (877.64 K)
Document Type: Original research articles
DOI: 10.21608/jfcr.2021.181031
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Authors
Amira Ahmed Elwazir email orcid 1; Ola Mohamed Fahmy2; Sameh Mahmoud Nabih3
1Operative Department, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt
2Professor of Operative Dentistry, Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt
3Professor of Operative Dentistry Vice-Dean of Postgraduate Studies and Research Faculty of Dentistry, Al-Azhar University - Boys Section, Cairo, Egypt
Abstract
Background: Deproteinizing enamel with sodium hypochlorite proved its positive effect when applied before one of the recent remineralizing agents (self-assembling peptide) which is considered an ideal enamel biomimetic approach. Objectives: To investigate the effect of sodium hypochlorite on the remineralizing capacity of the self-assembling peptide when applied before versus after acid etching of enamel; and the ability of the self-assembling peptide to sustain the remineralizing effect. Materials and Methods: Artificial enamel lesions were created on the proximal surfaces of 64 sample. Specimens were randomly put into two groups (N=32) according to NaOCl sequence of application (before/after acid etching). Group S1 (NaOCl applied before acid etching as recommended by the manufacturer); Group S2 (NaOCl applied after acid etching). After that, enamel samples were subjected to a pH-cycling for 1 month, followed by 3 months. Surface microhardness (SMH) was assessed at baseline, after demineralization, after remineralization, after pH-cycling for 1 month, and 3 months. SMH values were analyzed using ANOVA, the percentage of change of SMH was calculated based on the baseline SMH; the lower the value of the percentage of change the better the remineralizing capacity. Results: Upon comparing the values of percentage of change of microhardness at different timings we found that the lowest statistically significant percentage of change belonged to group S2. Conclusion: The sequence of NaOCl application had a statistically significant effect when applied after acid etching on the remineralization capacity of self-assembling peptide during different times of measuring leading to better re-hardening action and sustainable remineralizing action.
Keywords
Remineralization; self-assembling; peptide; deproteinization; microhardness
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