Impacts of sinonasal polyposis on pulmonary function pre and post function endoscopic surgery
Ismail, H., Mekhemar, S., Mostafs, S., Hafez, M. (2022). Impacts of sinonasal polyposis on pulmonary function pre and post function endoscopic surgery. EKB Journal Management System, 3(1), 45-52. doi: 10.21608/jram.2021.79281.1120
Hagar H Ismail; Sayed M Mekhemar; Soaad Y Mostafs; Manal R Hafez. "Impacts of sinonasal polyposis on pulmonary function pre and post function endoscopic surgery". EKB Journal Management System, 3, 1, 2022, 45-52. doi: 10.21608/jram.2021.79281.1120
Ismail, H., Mekhemar, S., Mostafs, S., Hafez, M. (2022). 'Impacts of sinonasal polyposis on pulmonary function pre and post function endoscopic surgery', EKB Journal Management System, 3(1), pp. 45-52. doi: 10.21608/jram.2021.79281.1120
Ismail, H., Mekhemar, S., Mostafs, S., Hafez, M. Impacts of sinonasal polyposis on pulmonary function pre and post function endoscopic surgery. EKB Journal Management System, 2022; 3(1): 45-52. doi: 10.21608/jram.2021.79281.1120

Impacts of sinonasal polyposis on pulmonary function pre and post function endoscopic surgery

Journal of Recent Advances in Medicine
Article 6, Volume 3, Issue 1, January 2022, Page 45-52  XML PDF (1005.57 K)
Document Type: Original Article
DOI: 10.21608/jram.2021.79281.1120
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Authors
Hagar H Ismail email 1; Sayed M Mekhemar2; Soaad Y Mostafs2; Manal R Hafezorcid 3
1Otorhinolaryngology Department, Road El-Farag General Hospital, Cairo, Egypt
2Otorhinolaryngology Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt
3Chest Diseases Department, Faculty of Medicine for Girls ,Cairo, Al-Azhar University, Egypt
Abstract
Background: the upper and lower airway form one contagious functional unit and exposed to same similar inflammatory stimuli that support hypothesis disease in one part could reflect or manifest on another.
Objective: to assess the effects of sinonasal polyposis on ventilatory function test pre and post functional endoscopic sinus surgery (FESS).
Methodology: This interventional randomized controlled clinical trial was carried out on 30 patients presented with chronic rhinosinusitis with nasal polyposis. All patients were subjected to nasal obstruction scale evaluation (NOSE) assessment, nasal endoscopic examination, Lund MacKay CT score and PFT pre and three months post FESS.
Results: there was a significant decrease of 2 items of NOSE scale (nasal obstruction and trouble sleeping), endoscopic examination score, and Lund MacKay CT score, with significant increase of PFT (FEV1 %, FVC %, FEV1\FVC ratio and FEF25-75%) three months post-operatively compared to preoperative values (p-value < 0.001). In the preoperative period 73.3% had an obstructive pattern in PFT while in the post-operative period only 36.6% had an obstructive pattern in PFT (p =0.004). By using multivariate logistic regression analysis, the most significant predictive factors of abnormal PFT in patients with sinonasal polyposis were right CT Lund MacKay scale (B= 0.74, p =0.014), left CT Lund MacKay scale (B= 0.56, p = 0.01), and total Lund MacKay CT score (0.4, p= 0.01).
Conclusions: the sinonasal polyposis have negative effects in PFTs that improved after FESS. The predictive factor for reduced PFTs in patients with sinonasal polyposis is Lund MacKay CT score.
Keywords
Nasal polyposis; pulmonary function tests; nose scale; Lund MacKay CT score
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