Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.
Abd El Maksoud, A., . Abd Allah, A., Ismail, M., Massoud, W. (2004). Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.. EKB Journal Management System, 15(1), 65-71. doi: 10.21608/ejhm.2004.18187
Awatif M. Abd El Maksoud; Asmaa M . Abd Allah; Mervat A. Ismail; Waleed Massoud. "Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.". EKB Journal Management System, 15, 1, 2004, 65-71. doi: 10.21608/ejhm.2004.18187
Abd El Maksoud, A., . Abd Allah, A., Ismail, M., Massoud, W. (2004). 'Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.', EKB Journal Management System, 15(1), pp. 65-71. doi: 10.21608/ejhm.2004.18187
Abd El Maksoud, A., . Abd Allah, A., Ismail, M., Massoud, W. Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.. EKB Journal Management System, 2004; 15(1): 65-71. doi: 10.21608/ejhm.2004.18187

Retinol and Alpha-Tocopherol Levels Among Hemodialysis Patients.

The Egyptian Journal of Hospital Medicine
Article 6, Volume 15, Issue 1, April 2004, Page 65-71  XML PDF (314.56 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2004.18187
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Authors
Awatif M. Abd El Maksoud1; Asmaa M . Abd Allah1; Mervat A. Ismail1; Waleed Massoud2
1Clinical Nutrition Department, National Nutrition Institute.
2Nephrology Department ,Ahmed Maher Teaching Hospital.
Abstract
Plasma retinol, alpha tocopherol, total cholesterol and triglycerides were measured in 40 patients aged 27-65 years, under regular hemodialysis (HD) for 1.8-13 years at Ahmed Maher teaching Hospital and in 28 healthy age and sex matched control. Predialysis and postdialysis measurements were also, done for a subset of 13 hemodialytic patients.
Among hemodialytic patients ,all values ( Plasma retinol ,alpha- tocopherol, total cholesterol and triglycerides )were significantly higher ( p < 0.05 ) with respect to healthy control .The ratio of retinol to total cholesterol was significantly higher , while alpha-tocopherol to total cholesterol ratio was insignificant .In almost all hemodialytic patients, plasma retinol was at toxic level (> 100 ug /dl) except for one patient .
On the other hand ,alpha-tocopherol level in hemodialytic patients was ranged between deficiency (<650 ug/dl ) in about 6 (15%) of them , marginal level (650-860 ug/dl ) at 3 ( 8% ) , while 9 (23%) had normal level (860-1080ug/ dl) and the rest 22 (54% ) were in the optimum level (> 1080 ug/dl). Comparing predialysis and postdialysis measurements , the hemodialytic patients showed non significant difference concerning retinol level , while alpha tocopherol was significantly decreased in postdialytic state .In conclusion ; further studies are needed to answer, if hemodialytic patients are at risk for symptomatic vitamin A toxicity?. Even with normal or low plasma vitamin E, it is needed as an antioxidant accessory therapy in hemodialytic patients.
 
Keywords
Hemodialysis; retinol; alpha-tocopherol; triglycerides total cholesterol
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