SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 4, Volume 8, Issue 1, June 1999, Page 23-27 PDF (2.09 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.1999.184162 | ||||
View on SCiNiTO | ||||
Authors | ||||
El-Sayed Lashine 1; Sobhy El-Adl2; Kamel Metwally3; Mansour Abou-Kull4 | ||||
1Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||||
2Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazige University, Zagazig, Egypt | ||||
3Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig. Egypt | ||||
4Medicinal Chemistry Department, Faculty of Pharmacy, University of Zagazig, Zagazig, Egypt | ||||
Abstract | ||||
A series of quinolinoxymethyl triazole (5), oxadiazole (6,8), isoxazolidin-3,5-diones (10), pyrazolidin-3,5-diones (11a,b) and other related pyrimidin-2,4,6-triones (12,) and pyrimidin-4,6-dione-2-thiones (12a) were synthesized. Four of the synthesized compounds were tested for antimicrobial activity; two of them displayed high activity against a variety of bacterial strains. | ||||
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