SPECTROPHOTOMETRIC ESTIMATION OF SOME NITROGENOUS PHARMACEUTICAL COMPOUNDS BY CHARGE TRANSFER COMPLEXATION
Ayad, M., Khalil, H., El-Henawee, M., Hosny, M. (1999). SPECTROPHOTOMETRIC ESTIMATION OF SOME NITROGENOUS PHARMACEUTICAL COMPOUNDS BY CHARGE TRANSFER COMPLEXATION. EKB Journal Management System, 8(1), 60-67. doi: 10.21608/zjps.1999.184167
Magda Ayad; Hawa Khalil; Magda El-Henawee; Mervat Hosny. "SPECTROPHOTOMETRIC ESTIMATION OF SOME NITROGENOUS PHARMACEUTICAL COMPOUNDS BY CHARGE TRANSFER COMPLEXATION". EKB Journal Management System, 8, 1, 1999, 60-67. doi: 10.21608/zjps.1999.184167
Ayad, M., Khalil, H., El-Henawee, M., Hosny, M. (1999). 'SPECTROPHOTOMETRIC ESTIMATION OF SOME NITROGENOUS PHARMACEUTICAL COMPOUNDS BY CHARGE TRANSFER COMPLEXATION', EKB Journal Management System, 8(1), pp. 60-67. doi: 10.21608/zjps.1999.184167
Ayad, M., Khalil, H., El-Henawee, M., Hosny, M. SPECTROPHOTOMETRIC ESTIMATION OF SOME NITROGENOUS PHARMACEUTICAL COMPOUNDS BY CHARGE TRANSFER COMPLEXATION. EKB Journal Management System, 1999; 8(1): 60-67. doi: 10.21608/zjps.1999.184167

SPECTROPHOTOMETRIC ESTIMATION OF SOME NITROGENOUS PHARMACEUTICAL COMPOUNDS BY CHARGE TRANSFER COMPLEXATION

Zagazig Journal of Pharmaceutical Sciences
Article 8, Volume 8, Issue 1, June 1999, Page 60-67  XML PDF (4.05 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1999.184167
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Authors
Magda Ayad email 1; Hawa Khalil2; Magda El-Henawee3; Mervat Hosny1
1Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University. Zagazig. Egypt.
2Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
3Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig. Egypt
Abstract
Three simple and sensitive colorimetric methods have been developed for the estimation of trazodone, timolol and piribedil through electron transfer complexation reaction. The methods involve the reaction of these drugs as p-donors with either n-electron acceptors P-chloronilic acid (PCA) and tetracyano-quinodimethane (TCNQ) and iodine as acceptor to give a stable and highly coloured radical anion. The coloured products were measured spectrophotometrically. The optimization of the different experimental conditions has been studied. The suggested methods were applied to assay the tested compounds in their pharmaceutical preparations. The results obtained agreed well with the reference methods.
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