SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL
Abdel-Rahman, S., Eissa, A., Ameen, N., Naglah, A. (1998). SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL. EKB Journal Management System, 7(2), 27-32. doi: 10.21608/zjps.1998.184796
Somaya Abdel-Rahman; Abdel-Monem Eissa; Nadia Ameen; Ahmed Naglah. "SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL". EKB Journal Management System, 7, 2, 1998, 27-32. doi: 10.21608/zjps.1998.184796
Abdel-Rahman, S., Eissa, A., Ameen, N., Naglah, A. (1998). 'SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL', EKB Journal Management System, 7(2), pp. 27-32. doi: 10.21608/zjps.1998.184796
Abdel-Rahman, S., Eissa, A., Ameen, N., Naglah, A. SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL. EKB Journal Management System, 1998; 7(2): 27-32. doi: 10.21608/zjps.1998.184796

SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL

Zagazig Journal of Pharmaceutical Sciences
Article 4, Volume 7, Issue 2, December 1998, Page 27-32  XML PDF (2.73 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1998.184796
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Authors
Somaya Abdel-Rahman email 1; Abdel-Monem Eissa1; Nadia Ameen2; Ahmed Naglah1
1Chemistry Dept., Faculty of Science, Zagazig University, Egypt.
2Chemistry Department, Girls College for Education, Jeddah, K.S.A
Abstract
In order to obtain peptide based amphoteric surfactants with antimicrobial activity, six polyethylene glycol bounded peptide chains were synthesized using the liquid phase method. The investigated chains contain aliphatic and aromatic amino acids in different sequences. Polyethylene glycol monomethyl ether was empolyed as soluble polymeric support; dicyclohexyl carbodiimide was used as the coupling reagent while the acid labile tert. butyloxy carbonyl group was applied in N-protection. The synthesized peptide chains was found to have promising surface properties beside their antimicrobial activity.
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