LIPID PROFILE IN EXPERIMENTAL DIABETES AS A PROMOTING FACTOR IN THROMBOSIS
El-Sweidy, M., Asker, M., Abdalla, F., Mosallamy, H. (1997). LIPID PROFILE IN EXPERIMENTAL DIABETES AS A PROMOTING FACTOR IN THROMBOSIS. EKB Journal Management System, 6(2), 23-29. doi: 10.21608/zjps.1997.184939
Mohamed El-Sweidy; Mervat Asker; Fatma Abdalla; Hala Mosallamy. "LIPID PROFILE IN EXPERIMENTAL DIABETES AS A PROMOTING FACTOR IN THROMBOSIS". EKB Journal Management System, 6, 2, 1997, 23-29. doi: 10.21608/zjps.1997.184939
El-Sweidy, M., Asker, M., Abdalla, F., Mosallamy, H. (1997). 'LIPID PROFILE IN EXPERIMENTAL DIABETES AS A PROMOTING FACTOR IN THROMBOSIS', EKB Journal Management System, 6(2), pp. 23-29. doi: 10.21608/zjps.1997.184939
El-Sweidy, M., Asker, M., Abdalla, F., Mosallamy, H. LIPID PROFILE IN EXPERIMENTAL DIABETES AS A PROMOTING FACTOR IN THROMBOSIS. EKB Journal Management System, 1997; 6(2): 23-29. doi: 10.21608/zjps.1997.184939

LIPID PROFILE IN EXPERIMENTAL DIABETES AS A PROMOTING FACTOR IN THROMBOSIS

Zagazig Journal of Pharmaceutical Sciences
Article 5, Volume 6, Issue 2, December 1997, Page 23-29  XML PDF (5.6 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1997.184939
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Authors
Mohamed El-Sweidy email 1; Mervat Asker2; Fatma Abdalla2; Hala Mosallamy2
1Biochemistry Dept., Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
2Department of Biochemistry, Faculty of Pharmacy, University of Zagazig, Egypt
Abstract
Hyperglycemia has a role in development of tissue hypoxia, a reasonable and a significant factor in atherogenesis. The persent study evaluates this diabetic complications through determination of Glycosylated hemogiobin AI (GHBA1), total cholesterol (Tc), high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC), triglyceride (TG), malondialdehyde in erythrocytes membrane (RBCS MDA), Lipoprotein (a) Lp(a)), platelet cholesterol/phospholipid ratio (C/P ratio), fibrinogen, antithrombin II (AT III) and plasminogen. Streptozotocin (STZ) diabetic rats were compared with normal rats. STZ induced significant increase in glucose, GHBA1, Tc, LDLC, Lp(a), RBCS MDA, fibrinogen, plasmirgen and C/P ratio. On the other hand, it significantly decreased the HDLc and AT III This study aimed to correlate blood coagulation factors and changes in lipid and lipoproteins in diabetes mellitus.
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