PHYTOCHEMICAL STUDY AND BIOASSAY OF SOME CONSTITUENTS FROM HELIOTROPIUM BACCIFERUM FORSSK | ||
Zagazig Journal of Pharmaceutical Sciences | ||
Article 12, Volume 6, Issue 2, December 1997, Pages 74-80 PDF (4.97 M) | ||
Document Type: Original Article | ||
DOI: 10.21608/zjps.1997.184946 | ||
Authors | ||
Taha Sarg* 1; Abdel-Monem Ateya2; Nawal Farrag3; Ehsan Abd El- aziz4; Azza El-Shafae5 | ||
1Department of Pharmacognosy, Faculty of Pharmacy, University of Zagazig, Egypt. | ||
2Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||
3Pharmacognosy Department, Faculty of Pharmacy, University of Zagazig , Zagazig , Egypt | ||
4Department of Pharmacognosy, Faculty of Pharmacy University of Zagazig, Egypt | ||
5Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt. | ||
Abstract | ||
Heliotropium bacciferum forssk (Boraginaceae) was found to contain heleurine N-oxide, heliotrine N-oxide and europine N-OXide as well as B-amyrin, B-sitosterol, B-sitosterol-O-glucoside. A new preparative HPLC method for the isolation of Pas N-oxides was developed. The expected cytotoxic activities were determined by the brine shrimp bioassay to measure their toxic activities and potential cytotoxicity. | ||
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