ONE POT SYNTHESIS, OF 2(1H)-QUINAZOLINONE DERIVATIVES | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 4, Volume 6, Issue 1, June 1997, Page 21-25 PDF (3.74 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.1997.184950 | ||||
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Author | ||||
Zakaria Abd El-Samii | ||||
Department of Organic Pharmaceutical Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||||
Abstract | ||||
Condensation of (3-methoxyphenyl)urea or guanidine derivatives (la-e) with a variety of acyl chlorides in polyphosphoric acid leads to intramolecular cyclization with formation of the title compounds (2a-j). Attempted one pot preparation of new tricyclic pyrrolo [3,2,1-ij]-2(2H)-quinazolinone derivatives (3) using (1f) carboxamidoindoline (1f) and acyl chlorides were carried out. | ||||
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