SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION
Metwally, M. (1997). SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION. EKB Journal Management System, 6(1), 33-40. doi: 10.21608/zjps.1997.184952
Mamdouh Metwally. "SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION". EKB Journal Management System, 6, 1, 1997, 33-40. doi: 10.21608/zjps.1997.184952
Metwally, M. (1997). 'SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION', EKB Journal Management System, 6(1), pp. 33-40. doi: 10.21608/zjps.1997.184952
Metwally, M. SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION. EKB Journal Management System, 1997; 6(1): 33-40. doi: 10.21608/zjps.1997.184952

SPECTROPHOTOMETRIC DETERMINATION OF QUINIDINE SULFATE BY ION-PAIR FORMATION

Zagazig Journal of Pharmaceutical Sciences
Article 6, Volume 6, Issue 1, June 1997, Page 33-40  XML PDF (3.95 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1997.184952
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Author
Mamdouh Metwally email
Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig- Egypt.
Abstract
A simple method for the determination of quinidine sulfate in tablets is based on the formation of an ion-pair between quinidine Comand thymol blue (TB) at pH=5.5 in aqueous-methanol solution. The absorbance of the ion-pair formed is measured and the Colncentration of the drug is calculated. The molar ratio of the ion-pair is determined and found to be 2:1 and with general formula [Q]+4 2.[T.B]-1 SO4-2 HSO4-1 as  calculated by elemental analysis. Using the present method quinidine sulfate in tablets was assayed. The results were statistically compared with those obtained by the official method.
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