SOME BIOCHEMICAL CHANGES IN PATIENTS WITH BACTERIAL MENINGITIS | ||||
| Zagazig Journal of Pharmaceutical Sciences | ||||
| Article 8, Volume 5, Issue 1, June 1996, Page 50-58 PDF (7.36 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zjps.1996.185054 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Hussein Ghaleb  1; Faten Zahran2; Ahmed El-Kholy3; Kariman El-Deeb4
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| 1Biochemistry Department, Faculty of Science, Mansura University, Egypt. | ||||
| 2Chemistry Department, Faculty of Science, Zagazig University , Egypt | ||||
| 3Biochemistry Department, Faculty of Medicine, Mansura University, Egypt | ||||
| 4Biochemistry Department, Faculty of Science, Mansura University, Egypt | ||||
| Abstract | ||||
| Gamma glutamyl transferase (GGT) and true cholinesterase, as well as each of the amino acids (glutamine, aspartic acid, glutamic acid, glycine, tyrosine, phenylalanine, histidine and tryptophan), except for gamma amino butyric acid (GABA) activity were significantly increased P≤0.001 in cerebrospinal fluid (CSF) of patients with bacterial meningitis (B.M). No change was observed in CSF electrolytes such as Sodium, calcium and magnesium except for potassium which was significantly increased P≤0.001 in patients with B.M as compared to healthy controls. Serum GGT activity was significantly elevated P≤0.001 in patients while serum true cholinesterase activity was significantly decreased p≤0.05 in patients with B.M. No change was observed in serum amino acids in patients with B.M as compared to healthy controls. | ||||
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