DETERMINATION OF NORFLOXACIN AND OFLOXACIN THROUGH CHARGE TRANSFER COMPLEXATION
El-Sadek, M., El-Shanawani, A., Ali, O. (1995). DETERMINATION OF NORFLOXACIN AND OFLOXACIN THROUGH CHARGE TRANSFER COMPLEXATION. EKB Journal Management System, 4(2), 33-39. doi: 10.21608/zjps.1995.185622
Mohamed El-Sadek; Abdalla El-Shanawani; Omar Ali. "DETERMINATION OF NORFLOXACIN AND OFLOXACIN THROUGH CHARGE TRANSFER COMPLEXATION". EKB Journal Management System, 4, 2, 1995, 33-39. doi: 10.21608/zjps.1995.185622
El-Sadek, M., El-Shanawani, A., Ali, O. (1995). 'DETERMINATION OF NORFLOXACIN AND OFLOXACIN THROUGH CHARGE TRANSFER COMPLEXATION', EKB Journal Management System, 4(2), pp. 33-39. doi: 10.21608/zjps.1995.185622
El-Sadek, M., El-Shanawani, A., Ali, O. DETERMINATION OF NORFLOXACIN AND OFLOXACIN THROUGH CHARGE TRANSFER COMPLEXATION. EKB Journal Management System, 1995; 4(2): 33-39. doi: 10.21608/zjps.1995.185622

DETERMINATION OF NORFLOXACIN AND OFLOXACIN THROUGH CHARGE TRANSFER COMPLEXATION

Zagazig Journal of Pharmaceutical Sciences
Article 6, Volume 4, Issue 2, December 1995, Page 33-39  XML PDF (2.72 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1995.185622
View on SCiNiTO View on SCiNiTO
Authors
Mohamed El-Sadek email 1; Abdalla El-Shanawani2; Omar Ali3
1Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt
2Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
3Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazig University, Egypt.
Abstract
A spectrophotometric method was described for the determination of the antibacterial quinolone derivative, norfloxacin and ofloxacin. Chloranilic acid was utilized for their determination, forming charge transfer complex with Amax. 517 and 520 for norfloxacin and ofloxacin, respectively. The optimum conditions of the reaction were discussed. The proposed method was applied for the determination of Noroxin and Tarivid tablets with means percentage accuracies, 100.7 ± 2.08 and 102.13 ± 2.08, respectively. Statistical analysis showed no significant difference between the proposed and official methods.
Statistics
Article View: 89
PDF Download: 90