INHIBITION OF PROPHAGE INDUCTION BY SYNTHETIC PENTAPEPTIDE
Abdel-Rahman, S., El daidamony, G. (1995). INHIBITION OF PROPHAGE INDUCTION BY SYNTHETIC PENTAPEPTIDE. EKB Journal Management System, 4(2), 57-61. doi: 10.21608/zjps.1995.185628
Somaya Abdel-Rahman; Gamal El daidamony. "INHIBITION OF PROPHAGE INDUCTION BY SYNTHETIC PENTAPEPTIDE". EKB Journal Management System, 4, 2, 1995, 57-61. doi: 10.21608/zjps.1995.185628
Abdel-Rahman, S., El daidamony, G. (1995). 'INHIBITION OF PROPHAGE INDUCTION BY SYNTHETIC PENTAPEPTIDE', EKB Journal Management System, 4(2), pp. 57-61. doi: 10.21608/zjps.1995.185628
Abdel-Rahman, S., El daidamony, G. INHIBITION OF PROPHAGE INDUCTION BY SYNTHETIC PENTAPEPTIDE. EKB Journal Management System, 1995; 4(2): 57-61. doi: 10.21608/zjps.1995.185628

INHIBITION OF PROPHAGE INDUCTION BY SYNTHETIC PENTAPEPTIDE

Zagazig Journal of Pharmaceutical Sciences
Article 10, Volume 4, Issue 2, December 1995, Page 57-61  XML PDF (3.38 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1995.185628
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Authors
Somaya Abdel-Rahman email 1; Gamal El daidamony2
1Chemistry Dept., Faculty of Science, Zagazig University, Egypt.
2Department of Botany Faculty of Science, University of Zagazig, Egypt.
Abstract
Six peptide chains different in length and sequences were synthesized by continuous flow solid phase method. Their effects on prophage induction were tested. It was found out that a pentapeptide at concentration of 25 µg/ml inhibited the spontaneous induction of prophage Lambda in E. coli strain W 3110 () and (0)RL7 s in R. Leguminosarum (lysogenic local isolate) by (99.5%) and (98.5%), respectively. This concentration was also able to inhibit the replication of the developed phages in the indicator strains. it is suggested that the peptide may block the receptor sites of the induced phages or inhibit Rec A Protease.
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