ALTERED HEPATIC FUNCTION CONSEQUENT TO IVERMECTIN TREATMENT IN RAMS
Hassan, H., Nasser, M., Abd El-Malak, M., Emara, S. (1995). ALTERED HEPATIC FUNCTION CONSEQUENT TO IVERMECTIN TREATMENT IN RAMS. EKB Journal Management System, 4(2), 72-75. doi: 10.21608/zjps.1995.185631
Hany Hassan; Mohamed Nasser; Mary Abd El-Malak; Samira Emara. "ALTERED HEPATIC FUNCTION CONSEQUENT TO IVERMECTIN TREATMENT IN RAMS". EKB Journal Management System, 4, 2, 1995, 72-75. doi: 10.21608/zjps.1995.185631
Hassan, H., Nasser, M., Abd El-Malak, M., Emara, S. (1995). 'ALTERED HEPATIC FUNCTION CONSEQUENT TO IVERMECTIN TREATMENT IN RAMS', EKB Journal Management System, 4(2), pp. 72-75. doi: 10.21608/zjps.1995.185631
Hassan, H., Nasser, M., Abd El-Malak, M., Emara, S. ALTERED HEPATIC FUNCTION CONSEQUENT TO IVERMECTIN TREATMENT IN RAMS. EKB Journal Management System, 1995; 4(2): 72-75. doi: 10.21608/zjps.1995.185631

ALTERED HEPATIC FUNCTION CONSEQUENT TO IVERMECTIN TREATMENT IN RAMS

Zagazig Journal of Pharmaceutical Sciences
Article 13, Volume 4, Issue 2, December 1995, Page 72-75  XML PDF (3.2 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1995.185631
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Authors
Hany Hassan email 1; Mohamed Nasser2; Mary Abd El-Malak3; Samira Emara3
1Animal Reproduction research Institute, P.O. 12556 EL-Haram, Giza, Egypt
2Faculty of Veterinary Medicine, Tanta University, Kafr El Sheikh branch, Egypt
3Animal Reproduction Research Institute, P.O box 12556, El-Haram, Giza, Egypt,
Abstract
This work was carried out on twelve clinically healthy adult Barki rams, divided into two equal groups. The first one was served as control and each animal of the second group was injected subcutaneously with one dose of 0.2 mg ivermectin /Kg body weight. Ivermectin treated group revealed a significant elevation in blood serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, isocitrate dehydrogenase, gamma glutamyl transferase, arginase, sorbitol dehydrogenase and total cholesterol. Meanwhile, ivermectin did not evoke any significant alteration in serum urea and creatinine levels. A very important conclusion that appears to be surfacing from the previous results is that this study represent further image of the hazardous effect of ivermectin in rams. Ivermectin inflected deleterious effects reflected as hepatic dysfunction.
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