Association Of Obesity With Relapsing Remitting Multiple Sclerosis Disability In Zagazig University Hospitals.
Fahmi, R., El Ebeary, M., Abdalrasheed, E., Elkhatib, T. (2023). Association Of Obesity With Relapsing Remitting Multiple Sclerosis Disability In Zagazig University Hospitals.. EKB Journal Management System, 29(1.1), 242-247. doi: 10.21608/zumj.2021.76659.2235
Rasha Mohamed Fahmi; Mahmoud El Sayed El Ebeary; Esraa Mohamed Abdalrasheed; Takwa Mohamed Elkhatib. "Association Of Obesity With Relapsing Remitting Multiple Sclerosis Disability In Zagazig University Hospitals.". EKB Journal Management System, 29, 1.1, 2023, 242-247. doi: 10.21608/zumj.2021.76659.2235
Fahmi, R., El Ebeary, M., Abdalrasheed, E., Elkhatib, T. (2023). 'Association Of Obesity With Relapsing Remitting Multiple Sclerosis Disability In Zagazig University Hospitals.', EKB Journal Management System, 29(1.1), pp. 242-247. doi: 10.21608/zumj.2021.76659.2235
Fahmi, R., El Ebeary, M., Abdalrasheed, E., Elkhatib, T. Association Of Obesity With Relapsing Remitting Multiple Sclerosis Disability In Zagazig University Hospitals.. EKB Journal Management System, 2023; 29(1.1): 242-247. doi: 10.21608/zumj.2021.76659.2235

Association Of Obesity With Relapsing Remitting Multiple Sclerosis Disability In Zagazig University Hospitals.

Zagazig University Medical Journal
Article 34, Volume 29, Issue 1.1, January 2023, Page 242-247  XML PDF (269.77 K)
Document Type: Original Article
DOI: 10.21608/zumj.2021.76659.2235
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Authors
Rasha Mohamed Fahmiorcid 1; Mahmoud El Sayed El Ebeary2; Esraa Mohamed Abdalrasheed email 3; Takwa Mohamed Elkhatib2
1Neurology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt
2Neurology Department, Faculty of Medicine, Zagazig University; Sharkia, Egypt
3Neurology Department, Faculty of medicine, Zagazig University;Sharkia, Egypt
Abstract
Background:Previous studies had linked obesity to the pathogenesis and risk of multiple sclerosis (MS) but little is known about its association with disease course. Objective: This study aimed to assess the frequency of obesity in MS patients and its relation to disease disability. Methods: A cross-section study included 60 patients with clinically definite relapsing remitting multiple sclerosis was selected from the inpatients wards and outpatients clinic of Neurology Department, Zagazig during the period from March 2020 to September 2020. All patients underwent a thorough physical and neurological examination, as well as laboratory and radiographic tests. Obesity was diagnosed if body mass index (BMI) ≥30. The Expanded Disability Status Scale (EDSS) was used to assess disease disability. Patients were divided into 2 groups (obese and non-obese) according to BMI. Results: Obesity frequency was 43.3% (26 MS patients). Obese MS patients had higher disease duration (6.23 ± 4.65) and more disease disability (EDSS= 4.0 ± 2.21). There was positive correlation between BMI with EDSS, disease duration, number of relapses and total cholesterol. Multiple regression analysis showed that EDSS was independently associated with obesity in MS patients.Conclusion:There was a high frequency of obesity in MS patients. Disease disability (EDSS) was significantly associated with obesity in MS patients. Obesity screening should be a regular component of MS management.
Keywords
Multiple Sclerosis; Obesity; Disability; EDSS; BMI
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