Vitamin D Assessment in Diabetic patients with Peripheral Neuropathy
Sadek, N., Assy, M., Zaghlol, A., Hamed, M. (2023). Vitamin D Assessment in Diabetic patients with Peripheral Neuropathy. EKB Journal Management System, 29(2), 411-416. doi: 10.21608/zumj.2021.71822.2190
Nashwa Abo Farrag Sadek; Mohamed Hamdy Assy; Ahmed A. Zaghlol; Mohamed Gaber Hamed. "Vitamin D Assessment in Diabetic patients with Peripheral Neuropathy". EKB Journal Management System, 29, 2, 2023, 411-416. doi: 10.21608/zumj.2021.71822.2190
Sadek, N., Assy, M., Zaghlol, A., Hamed, M. (2023). 'Vitamin D Assessment in Diabetic patients with Peripheral Neuropathy', EKB Journal Management System, 29(2), pp. 411-416. doi: 10.21608/zumj.2021.71822.2190
Sadek, N., Assy, M., Zaghlol, A., Hamed, M. Vitamin D Assessment in Diabetic patients with Peripheral Neuropathy. EKB Journal Management System, 2023; 29(2): 411-416. doi: 10.21608/zumj.2021.71822.2190

Vitamin D Assessment in Diabetic patients with Peripheral Neuropathy

Zagazig University Medical Journal
Article 3, Volume 29, Issue 2, March 2023, Page 411-416  XML PDF (440.7 K)
Document Type: Original Article
DOI: 10.21608/zumj.2021.71822.2190
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Authors
Nashwa Abo Farrag Sadek email orcid 1; Mohamed Hamdy Assyorcid 1; Ahmed A. Zaghlolorcid 2; Mohamed Gaber Hamedorcid 3
1Internal Medicine Department, Zagazig University, Egypt
2Internal medicine Department, Zagazig university
3Department of internal medicine, faculty of medicine, zagazig university
Abstract
Background: The diabetes mellitus (DM) prevalence was 525 million in 2019 and type 2 (T2DM) around 90% of all cases of diabetes. Diabetic neuropathy (DN) is a micro-vascular complication of DM and considered a major cause of mortality and morbidity in diabetic population. The aim of this study to evaluate the relation between a possible vitamin D level and diabetic neuropathy development. Patient and methods: A study included 80 patients divided into 4 groups; (A): diabetic patients with painful diabetic neuropathy; (B): diabetic patients with painless diabetic neuropathy; (C): diabetic patients with painless neuropathy and neuropathic ulcer and (D) healthy controls. Serum vitamin D levels was measured in all patients and neurological scoring for neuropathy was assessed. Results: Patients In group A had neuropathy score from 9 to 15. Patients in group B had Neuropathy score from 7 to14. In group C, patients had neuropathy score from 6 to 9. 60% of group A had deficient vitamin d level. 65% of group B of had deficient vitamin d level. 5% only of the studied healthy control had deficient vitamin D. There was highly statistically significant difference between the four groups regarding vitamin D level and vitamin D status assuming that vitamin D deficiency was below 25 ng/dl. Conclusion: Vitamin D deficiency is considered as major risk factor for development of diabetic peripheral neuropathy (DNP). Therefore, we recommended to estimate vitamin D level in patients with DPN.
Keywords
Diabetes mellitus, Vitamin D, Neuropathic Ulcer; Peripheral Neuropathy
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