PMR DETERMINATION OF PRAZIQUANTEL | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 21, Volume 4, Issue 2, December 1995, Page 135-142 PDF (3.18 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.1995.186264 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mamdouh Metwally 1; Abdallah El-Shanawany2; Abd El-Aziz Bayomi3; Mohsin El-Zareh4 | ||||
1Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt. | ||||
2Department of Medicinal Chemistry, Faculty of Pharmacy, Zagazige University, Zagazig, Egypt | ||||
3Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt. | ||||
4Department of Chemistry, Faculty of Science, Zagazig University, Egypt. | ||||
Abstract | ||||
Pmr techniques have been used for the determination of praziquantel as sum integeral of the cyclohexane protons as multiplet that appear at 1.1-2 ppm and as compared to the sum integeral of the 1,4-disubstituted aromatic protons system as doublet of doublet that appear at 7.5-8.5 ppm using N,N-dimethylaminobenzaldehyde as internal standard. The obtained results shows % recovery of mean average 100.39. The method is valid for the determination of praziquantel in tablet and in presence of its induced degradation products. | ||||
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