DETERMINATION OF PHENOBARBITONE IN TWO AND THREE COMPONENTS FORMULATIONS BY FIRST AND SECOND DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRY | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 16, Volume 4, Issue 1, June 1995, Page 117-125 PDF (4.15 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.1995.186368 | ||||
View on SCiNiTO | ||||
Authors | ||||
Hesham Salem 1; Afaf Aboul Kheir2 | ||||
1MiST Pharmacy. Menia El-Kamh, Sharkia, Eqypt. | ||||
2Chemistry Department, Girls College (Scientific Departments) Riyadh, Saudi Arabia | ||||
Abstract | ||||
Phenobarbitone has been determined in a ternary mixture with oxyphenonium bromide and meprobamate (mixture A) and in binary mixtures with paracetamol (mixture B) or acetylsalicylic acid (mixture C) using derivative spectrophotometry applying zero-crossing technique of measurement. The combining active ingredients have also been determined. The procedures were proved using laboratory prepared mixtures and their utility in assay of pharmaceutical dosage forms were also presented. | ||||
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