ESSENTIAL OIL AND LIPIDS OF NIGELLA SATIVA SEED AND THEIR BIOLOGICAL ACTIVITY
Karawya, M., Hashim, F., Abd El-Wahab, S., EI-Deeb, K., Soliman, S., Salam, I., Mokhtar, N., El-Hossiny, S. (1994). ESSENTIAL OIL AND LIPIDS OF NIGELLA SATIVA SEED AND THEIR BIOLOGICAL ACTIVITY. EKB Journal Management System, 3(2), 49-57. doi: 10.21608/zjps.1994.186443
Mohamed Karawya; Fayek Hashim; Samia Abd El-Wahab; Kadriya EI-Deeb; Suzan Soliman; Ibrahim Salam; Nadia Mokhtar; Somaya El-Hossiny. "ESSENTIAL OIL AND LIPIDS OF NIGELLA SATIVA SEED AND THEIR BIOLOGICAL ACTIVITY". EKB Journal Management System, 3, 2, 1994, 49-57. doi: 10.21608/zjps.1994.186443
Karawya, M., Hashim, F., Abd El-Wahab, S., EI-Deeb, K., Soliman, S., Salam, I., Mokhtar, N., El-Hossiny, S. (1994). 'ESSENTIAL OIL AND LIPIDS OF NIGELLA SATIVA SEED AND THEIR BIOLOGICAL ACTIVITY', EKB Journal Management System, 3(2), pp. 49-57. doi: 10.21608/zjps.1994.186443
Karawya, M., Hashim, F., Abd El-Wahab, S., EI-Deeb, K., Soliman, S., Salam, I., Mokhtar, N., El-Hossiny, S. ESSENTIAL OIL AND LIPIDS OF NIGELLA SATIVA SEED AND THEIR BIOLOGICAL ACTIVITY. EKB Journal Management System, 1994; 3(2): 49-57. doi: 10.21608/zjps.1994.186443

ESSENTIAL OIL AND LIPIDS OF NIGELLA SATIVA SEED AND THEIR BIOLOGICAL ACTIVITY

Zagazig Journal of Pharmaceutical Sciences
Article 6, Volume 3, Issue 2, December 1994, Page 49-57  XML PDF (5.21 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1994.186443
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Authors
Mohamed Karawya email 1; Fayek Hashim1; Samia Abd El-Wahab1; Kadriya EI-Deeb1; Suzan Soliman1; Ibrahim Salam2; Nadia Mokhtar3; Somaya El-Hossiny3
1Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
2Cancer Pathology Department, National Cancer Institute, Cairo University, Cairo, Egypt
3Histopathology Department, National Cancer Institute, Cairo University, Cairo, Egypt
Abstract
The essential oil as well as the expressed oil of Nigella sativa L. seeds, were subjected to qualitative and quantitative studies employing different chromatographic techniques. Thymoquinone (ca 30%), p-cymene (ca 38%) and a-pinene (ca 14%) constituted the main make up of the essential oil. GLC revealed that the lipid portion of the expressed oil iss built-up mostly of stearic (ca 47%) and arachidic (ca 32%) acids beside lesser amounts of palmitic (ca 7%) and myristic (ca 4%) acids. a-amyrin, B-sitosterol and oleanolic acid were isolated from the unsaponifiable matter of the lipid portion. The expressed oil showed significant antimicrobial and antifungal activities. It could normalized the enzymatic disturbance in the liver tissue, previously produced by exposure to ionizing radiation. This radioprotective effect was supported by the morphological changes of liver tissues. The intestine showed minimal changes and no evidence of protection was observed for the kidneys.
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