DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 15, Volume 3, Issue 2, December 1994, Page 132-141 PDF (4.29 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.1994.186488 | ||||
View on SCiNiTO | ||||
Authors | ||||
Mohamed El Balkiny 1; Gamal Ragab2; Magda Ayad3 | ||||
1Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt | ||||
2Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt. | ||||
3Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University. Zagazig. Egypt. | ||||
Abstract | ||||
A simple and accurate charge-transfer complex (CT) method for the determination of trimethoprim is presented. The method involved the use of p-chloranil in dioxane: methanol (1:2) medium. The absorbance of the violet colour of the charge-transfer complex was measured at 535 nm against reagent blank. The method permits determination of about 60-480µg ml-1 of trimethoprim in the final solution mixture with mean percentage recovery 98.84± 1.23% | ||||
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