SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES
Ahmed, G. (1994). SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES. EKB Journal Management System, 3(2), 148-152. doi: 10.21608/zjps.1994.186590
Gamal Ahmed. "SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES". EKB Journal Management System, 3, 2, 1994, 148-152. doi: 10.21608/zjps.1994.186590
Ahmed, G. (1994). 'SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES', EKB Journal Management System, 3(2), pp. 148-152. doi: 10.21608/zjps.1994.186590
Ahmed, G. SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES. EKB Journal Management System, 1994; 3(2): 148-152. doi: 10.21608/zjps.1994.186590

SYNTHESIS OF NEW THIENO-[2,3-b]-PYRIDINE AND PYRAZOLO-5,4-b-PYRIDINE DERIVATIVES

Zagazig Journal of Pharmaceutical Sciences
Article 17, Volume 3, Issue 2, December 1994, Page 148-152  XML PDF (1.46 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1994.186590
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Author
Gamal Ahmed email
Chemistry Department, Faculty of Science, Zagazig University, Egypt.
Abstract
3-Cyano-4,6-dimethyl-2-pyridinethiol 1 was allowed to react with chloroacetone and hydrazine hydrate to give the corresponding thienopyridine derivative 2 and pyrazolopyridine derivative 5, respectively. Compound 2 reacted with aldehydes to yield 3a-3c. Reaction of compound 5 with thionyl chloride and arylidinemalononitriles gives 6 and 8a,b, respectively. Compound 6 reacted with benzil and p,p-dichlorobenzil to yield the corresponding benzilimine derivatives 7a,b.
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