BIOCHEMICAL AND HAEMATOLOGICAL STUDIES ON CADMIUM CHLORIDE ADMINISTRATION IN RAABITS | ||||
Zagazig Journal of Pharmaceutical Sciences | ||||
Article 17, Volume 3, Issue 1, June 1994, Page 123-130 PDF (4.41 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/zjps.1994.186711 | ||||
View on SCiNiTO | ||||
Author | ||||
Abdel-Aziz Diab | ||||
Zoology Department, Faculty of Science, Zagazig University, Egypt | ||||
Abstract | ||||
Cadmium chloride (0.5 mg/kg) was given intraperitoneally (i.p.) into mature male rabbits every other day for 5 weeks. The results showed a significant increase in serum total proteins. An increase in β and ɣ-globulins (P < 0.001) was observed. Serum ALT and AST activities were also increased in rabbits treated with cadmium and vaccinated with Clostridia antisera when compared with the vaccinated control group. Whereas, a globulins and serum urea nitrogen (SUN) were significantly decreased (P < 0.001). Blood gases analysis showed significant decreases (P < 0.05) in PCO2, HCO3 and TCO2 in the vaccinated treated group compared with the vaccinated control group. A marked increase (P < 0.001) was also recorded in eosinophils and monocytes counts of the vaccinated treated group compared with the vaccinated control group. | ||||
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