Study of skin expression of Micro RNA 203 in patients with Alopecia areata
ElRafaie, A., Sorour, N., .Mustafa, A., Elshimi, O., Alshleyan, S. (2019). Study of skin expression of Micro RNA 203 in patients with Alopecia areata. EKB Journal Management System, 1(1), 51-54. doi: 10.21608/bjas.2019.187075
A.M. ElRafaie; N.E. Sorour; A.I .Mustafa; O.S. Elshimi; S.F. Alshleyan. "Study of skin expression of Micro RNA 203 in patients with Alopecia areata". EKB Journal Management System, 1, 1, 2019, 51-54. doi: 10.21608/bjas.2019.187075
ElRafaie, A., Sorour, N., .Mustafa, A., Elshimi, O., Alshleyan, S. (2019). 'Study of skin expression of Micro RNA 203 in patients with Alopecia areata', EKB Journal Management System, 1(1), pp. 51-54. doi: 10.21608/bjas.2019.187075
ElRafaie, A., Sorour, N., .Mustafa, A., Elshimi, O., Alshleyan, S. Study of skin expression of Micro RNA 203 in patients with Alopecia areata. EKB Journal Management System, 2019; 1(1): 51-54. doi: 10.21608/bjas.2019.187075

Study of skin expression of Micro RNA 203 in patients with Alopecia areata

Benha Journal of Applied Sciences
Article 22, Volume 1, Issue 1, March 2016, Page 51-54  XML PDF (495.63 K)
DOI: 10.21608/bjas.2019.187075
View on SCiNiTO View on SCiNiTO
Authors
A.M. ElRafaie1; N.E. Sorour1; A.I .Mustafa1; O.S. Elshimi2; S.F. Alshleyan2
1Dermatology, Venereology and Andrology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
Abstract
Alopecia areata [AA] will be An as a relatable point hair passing condition that is described Eventually Tom's perusing intense onset about non-scarring hair misfortune for generally strongly characterized regions going starting with little patches will broad or lesquerella every now and again diffuse inclusion ,hair misfortune may be a critical reason for tension and inability. It need been broadly postulated that AA may be a organ particular immune system sickness for hereditary predisposition Furthermore an Ecological trigger. The part of microRNA [miRNA] done immune system maladies [AIMDs] may be from claiming uncommon vitality Concerning illustration skin lesions would a initial show fate to large portions for the individuals states. MiRNAs would little non-coding RNAs about more or less 22 nucleotides in length, which would made by the enzymatic cleavage of the endogenous essential transcripts, which hold An neighborhood clip structure, miR-203 may be communicated done differentiating units of the epidermis, hair follicle and sebaceous organ. The aim of this study was to investigate the role of miR-203 in patients with AA by assessment of its skin expression. This contemplate will incorporate 30 patients suffice starting with alopecia areata [Group An]. In addition, 20 Obviously sound people Similarly as An control bunch [Group B]. Constantly on patients will be chose from the outpatient facility for Dermatology, Venerology What's more Andrology division about Benha college healing centers. Punch biopsies were taken from each liable. MicroRNA-203 will make concentrated What's more assessed altogether tests utilizing RT-qPCR. Results: there might have been statistically huge distinction in level of miR-203 in patients from claiming AA contrasted with control gathering. AA patients hint at Exceptionally expanded level over miR-203 over tissue test clinched alongside think about with control assembly.
Keywords
Alopecia Areata; MicroRNA; miR-203
Statistics
Article View: 77
PDF Download: 211