Is Hysteroscopic Endometrial Scratching Affect Outcome of Intracytoplasmic Sperm Injection in Women with Primary Infertility?
Rezk, A., Elsherbiny, M., Salama, K., Souidan, I., Abd El-Menaem, M. (2019). Is Hysteroscopic Endometrial Scratching Affect Outcome of Intracytoplasmic Sperm Injection in Women with Primary Infertility?. EKB Journal Management System, 4(2), 117-124. doi: 10.21608/bjas.2019.187195
A.Y. Rezk; M.F. Elsherbiny; K.M. Salama; I.I. Souidan; M.M. Abd El-Menaem. "Is Hysteroscopic Endometrial Scratching Affect Outcome of Intracytoplasmic Sperm Injection in Women with Primary Infertility?". EKB Journal Management System, 4, 2, 2019, 117-124. doi: 10.21608/bjas.2019.187195
Rezk, A., Elsherbiny, M., Salama, K., Souidan, I., Abd El-Menaem, M. (2019). 'Is Hysteroscopic Endometrial Scratching Affect Outcome of Intracytoplasmic Sperm Injection in Women with Primary Infertility?', EKB Journal Management System, 4(2), pp. 117-124. doi: 10.21608/bjas.2019.187195
Rezk, A., Elsherbiny, M., Salama, K., Souidan, I., Abd El-Menaem, M. Is Hysteroscopic Endometrial Scratching Affect Outcome of Intracytoplasmic Sperm Injection in Women with Primary Infertility?. EKB Journal Management System, 2019; 4(2): 117-124. doi: 10.21608/bjas.2019.187195

Is Hysteroscopic Endometrial Scratching Affect Outcome of Intracytoplasmic Sperm Injection in Women with Primary Infertility?

Benha Journal of Applied Sciences
Article 17, Volume 4, Issue 2, March 2019, Page 117-124  XML PDF (669.04 K)
Document Type: Original Research Papers
DOI: 10.21608/bjas.2019.187195
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Authors
A.Y. Rezk1; M.F. Elsherbiny1; K.M. Salama1; I.I. Souidan1; M.M. Abd El-Menaem2
1Obstetrics and Gynecology Dept., Faculty of Medicine, Benha Univ., Benha, Egypt
2(MSCC), Benha Health Insurance, Ministry of Health, Egypt
Abstract
Implantation rate per embryo transferred usually does not exceed 30%, although higher rates with use of blastocysts have been reported, depending on age. Successful implantation depends on development of high-quality embryos and the acquisition of endometrial receptivity. Implantation failure is attributed to the failure of uterus to acquire receptivity. Implantation failure remains a major factor limiting success in vitro fertilization (IVF) treatment. Mechanical manipulation of the endometrium can enhance receptivity by modulating gene expression of factors required for implantation like glycodelin A, laminin alpha 4, integrin alpha 6 and matrix metalloproteinase 1.Value of hysteroscopic endometrial scratching in improving pregnancy rates in patient undergoing ICSI in the next cycle in a randomized controlled study.The study was carried out at the Benha Fertility Centre, including 91 infertile patients as eligible cases for the study and recruited for hysteroscopic endometrial scratching in early follicular phase of the cycle between the 7th and 11th day of the cycle and 91 women as a control group without endometrial scratching.Our results had showed non-significant differences between case group and control group regarding age, body mass index and duration. There were non-significant differences between interventional group and non-interventional group regarding number of follicles, number of oocytes retrieved, number of embryos, endometrial thickness, pregnancy rate, implantation rate and ongoing pregnancy and a high significant difference between the two studied groups regarding microbiota. Endometrial scratching does not result in   improving clinical pregnancy rates  and implantation rate in  the subsequent IVF-ET in women with primary infertility. 
  
Keywords
Implantation; Fertilizaion; Implantation Failure; Hysteroscopy; Endometrial Scratching
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