STUDY OF SERUM LEVEL OF L-CARNITINE IN CHILDREN WITH AUTISM SPECTRUM DISORDER | ||||
ALEXMED ePosters | ||||
Article 189, Volume 3, Issue 4, December 2021, Page 21-22 | ||||
Document Type: Preliminary preprint short reports of original research | ||||
DOI: 10.21608/alexpo.2021.89742.1242 | ||||
View on SCiNiTO | ||||
Author | ||||
Maha Salah Ibrahim | ||||
Department of Pediatrics, Faculty of Medicine, Alexandria University | ||||
Abstract | ||||
Autism Spectrum Disorder (ASD) is a disorder characterized by language, social and behavioral impairments. Its prevalence is increasing and researches to detect etiology are growing. It is defined by the American psychiatric association’s diagnosis and statistical manual of mental disorders (DSM-5) as a single disorder that includes disorders that were previously considered separate-autism, Asperger’s syndrome, childhood disintegrative disorder and pervasive developmental disorder not otherwise specified. Early diagnosis means early treatment and better prognosis and outcome. The search for ASD biomarkers for early diagnosis is growing. Several studies have detected mitochondrial dysfunction as a cause of ASD and L-carnitine level as a marker to the mitochondrial function. AIM OF THE WORK We aimed to study the role of serum level of L-carnitine in the pathogenesis of autism manifestations and using it as a biomarker for diagnosis of ASD and assess if there is a relation between it and ASD severity. and | ||||
Keywords | ||||
Autism Spectrum Disorder (ASD); DSM-5; Childhood autism rating scale (CARS) | ||||
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