SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS
Harraz, F., Farah, M., Abdel-Aziz, S. (1993). SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS. EKB Journal Management System, 2(1), 161-169. doi: 10.21608/zjps.1993.189000
Fathalla Harraz; Mohamed Farah; Sayed Abdel-Aziz. "SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS". EKB Journal Management System, 2, 1, 1993, 161-169. doi: 10.21608/zjps.1993.189000
Harraz, F., Farah, M., Abdel-Aziz, S. (1993). 'SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS', EKB Journal Management System, 2(1), pp. 161-169. doi: 10.21608/zjps.1993.189000
Harraz, F., Farah, M., Abdel-Aziz, S. SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS. EKB Journal Management System, 1993; 2(1): 161-169. doi: 10.21608/zjps.1993.189000

SUBCHRONIC EFFECTS OF THE ORAL ADMINISTRATION OF THE LYOPHILIZED AQUEOUS EXTRACT OF CHROZOPHORA VERBASCIFOLIA IN RATS

Zagazig Journal of Pharmaceutical Sciences
Article 16, Volume 2, Issue 1, June 1993, Page 161-169  XML PDF (4.35 MB)
Document Type: Original Article
DOI: 10.21608/zjps.1993.189000
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Authors
Fathalla Harraz email 1; Mohamed Farah2; Sayed Abdel-Aziz2
1Dept of Vet. Med., College of Agric. and Vet. Med., King Saud Univ., Qassim, Bureidah, Saudi Arabia
2Dept of Vet. Med., College of Agric. and Vet. Med., King Saud Univ., Qassim, Bureidah, Saudi Arabia
Abstract
Daily oral doses (400 mg/kg.b.wt.) of the lyophilized aqueous extract of C. verbascifolia were given to adult Wistar rats for a period of 4 weeks. The results revealed a significant decrease in cholesterol level (P<0.05) and inorganic phosphorus (P < 0.001), in addition to a marked increase (P < 0.001) in serum albumin and calcium. The haemogram showed a marked leucocytopenia, lymphocytopenia, decreased neutrophils, monocytes (P < 0.001) and basophils counts (P<0.05). Moreover, a significant increase (P<0.01) in MCH was also recorded. Changes in body and organ weights as well as histopathological findings were also discussed.
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