Evaluation of Ochratoxins in Lactating Mothers and its Transfer to Their Exclusively Breast-Fed Infants through Breast milk | ||||
| The Egyptian Journal of Hospital Medicine | ||||
| Article 9, Volume 85, Issue 1, October 2021, Page 2725-2729 PDF (466 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejhm.2021.189836 | ||||
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| Authors | ||||
| Mahmoud Mohamed Mohamed El-Sayed Mousa; Alaa Zidan Ibrahim; Mohamed Osman Hafez; Doaa Metwaly Abd Elmonem | ||||
| Abstract | ||||
| Background: Ochratoxin A (OTA) is a well-known widely-spread mycotoxin all over the world that constitutes a real human threat. Its presence in human milk has previously been reported in different countries. Objective: This study aimed to detect the presence of OTA in both mothers’ milk, sera, and infants’ sera and compare the results with a previous study done in Egypt. Patients and Methods: Forty-eight healthy breast-lactating mothers and their infants who were exclusively breast-fed for at least 4 months were included. All of them were subjected to a thorough laboratory evaluation including determination of OTA concentration by (ELISA) Enzyme-Linked Immunosorbent Assay. Results: Fifteen mothers (31.3%) and their infants had been contaminated with OTA. The analysis showed that all infants of affected mothers had OTA in their sera. Conclusion: Multivariate logistic regression analysis showed that there was a significant correlation between OTA levels in mothers’ sera, milk, and their infants’ sera. | ||||
| Keywords | ||||
| Human milk; Kidney functions; Lactation; Ochratoxin A- urinary NGAl | ||||
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