ANALYSIS OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND ANTAGONISTS | ||||
| Sphinx Journal of Pharmaceutical and Medical Sciences | ||||
| Volume 1, Issue 1, April 2021, Page 1-41 PDF (812.9 K) | ||||
| Document Type: Review articles | ||||
| DOI: 10.21608/sjpms.2021.190417 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Pakinaz Y Khashaba1, 2; Horria A Mohamed3; Reem Y Shahin  4
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| 1Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt. | ||||
| 2Analytical Chemistry, Faculty of Pharmacy, Sphinx University, New Assiut, Egypt. | ||||
| 3Analytical chemistry, Faculty of Pharmacy, Assiut, Egypt. | ||||
| 4Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, New Assiut , Egypt | ||||
| Abstract | ||||
| The Angiotensin-converting enzyme inhibitors and antagonists are widely used in the management of essential hypertension, stable chronic heart failure, myocardial infarction and diabetic nephropathy,so that specific and sensitive methods are needed for the qualitative and quantitative determinations of these drugs in pharmaceutical dosage forms and in biological material. In the last few years, there was no review published covering all different analytical methods used for the determination of these drugs. The aim of this work is to review the most important recent methods for their analysis in pure forms, in different pharmaceutical dosage forms and in biological fluids due to the great importance of this class of drugs. This review includes two parts: the first part presents the methods applied for the analysis of pharmaceuticals. The second part is devoted to the methods elaborated for the assays in biological material (blood, plasma and urine). | ||||
| Keywords | ||||
| Angiotensin converting enzyme inhibitors, Antagonists; Analytical methods; Pharmaceutical dosage forms analysis; Biological fluids analysis | ||||
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