EXPERIMENTAL STUDY UF HYPUTHYRUIDISM IN RATS T-— HDRPHUMETRICAL RND HISTUPRTHULUGICAL CHHNGES INTHE KIDNEY | ||||
| Assiut Veterinary Medical Journal | ||||
| Article 16, Volume 11.2, Issue 22, January 1984, Page 109-114 PDF (2.43 MB) | ||||
| Document Type: Research article | ||||
| DOI: 10.21608/avmj.1984.190837 | ||||
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| Author | ||||
| H.K. IBRAHIM | ||||
| Abstract | ||||
| The present study was designed to investigate the effect of experimental hypothyroidism induced by subcutaneous injection of rnethylthiouracil (M T U) on the morphological and morphometrical changes in the kidneys of rats. Fifty rats were used in this experiment. They were divided into Ii groups A,B,C and D which were treated by S/C. injection of (M U T) at dose level l0, 0,5 0,2 0,l mg. per Kg body weight respectively. ln addition, fifth group E of 10 animals was used as control. The morphometrical changes revealed that. l- The gromerular tuft is significantly decreased by administration of antithyroid drug. 2- lncrease in the muclear diameter in the first two groups. 3~ increase in the glomerular diameter in the first group. | ||||
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