RELATIVE AND DIFFERENTIAL COUNT OF PULMONARY CELLS OF GOLDEN HAMSTERS AFTER EXPOSURE TO SYNTHETIC DUST | ||||
| Assiut Veterinary Medical Journal | ||||
| Article 9, Volume 9, Issue 17.18, January 1982, Page 47-52 PDF (1.85 MB) | ||||
| Document Type: Research article | ||||
| DOI: 10.21608/avmj.1982.191548 | ||||
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| Authors | ||||
| K.S.A. EASA; A.S. EL-SHEIKH; G.A.R. KAMAR; M.S. SAMY | ||||
| Depts. of Animal Production, Faculties of Agriculture, Al-Azhar Univ., & Cairo univ., and National Research Center, Dokki, Giza, Egypt, | ||||
| Abstract | ||||
| The present work is focused on the evaluation on changes occuring in the relative and differential count of pulmonary cells of golden hamsters animals following acute inhalation exposure to synthetic dust which was p < /strong>rep < /strong>ared so as to simulate that p < /strong>rev ailing in sandy storms. The results revealed a positive correlation between the total count of p < /strong>ulmonary cells and the body weight of the animals. The exp < /strong>osure treatments showed that the relative, (in relation to 100 gm. body weight) and total pulmonary cell count in hamsters increases steadily as the p < /strong>eriod of exposure is prolonged. This increase continues up to 48 hours exp < strong>osure when the count was more than two folds than that of the control. After one and two months following the cessation of the inhalation experiments, clearance took place and the animals showed a drop in the total count down to a point close to the base line of the control. The differential count of p < /strong>ulmonary cells showed that the p < /strong>ercentage of lymphocyte cells was 0.66 for the control hamsters then reached 1.8, 16.5, 18.48 and 11.3 after exposure for 12, 24, 48 and 72 hours respectively.Pulmonary alveolar macrophage cells percentage was 99.34 for the controls, reached 98.2, 83.5, 81.52 and 88.7 after the mentioned exp < /strong>osure periods resp < /strong>ectively. Clearance for one and two months after the latter three exposure treatments resp < /strong>ectively decreased the lymp < /strong>hocyte cell p < /strong>ercent age than the none-cleared animals, the prolonged clearance gave the lower lymphocyte p < /strong>ercentages. The clearance periods p < /strong>reviously mentioned increased the pulmonary alv eolar macrophage percentages than the non-cleared animals. Values of p < /strong>ulmonary alv eolar macrophage increased with increasing clearance p < /strong>eriods. | ||||
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