The Relationship between Vitamin D level and incidence of Diabetic Peripheral Neuropathy in Diabetic patients type 2
Mahmoud, H., El-Azab, M., Butros, M., Mourad, A. (2021). The Relationship between Vitamin D level and incidence of Diabetic Peripheral Neuropathy in Diabetic patients type 2. EKB Journal Management System, 38(3), 908-924. doi: 10.21608/bmfj.2021.21906.1200
Hind Mohamed Mohamed Mahmoud; Mohamed Hammad El-Azab; Maged Kamal Fahim Butros; AbdelNaser Ali Mourad. "The Relationship between Vitamin D level and incidence of Diabetic Peripheral Neuropathy in Diabetic patients type 2". EKB Journal Management System, 38, 3, 2021, 908-924. doi: 10.21608/bmfj.2021.21906.1200
Mahmoud, H., El-Azab, M., Butros, M., Mourad, A. (2021). 'The Relationship between Vitamin D level and incidence of Diabetic Peripheral Neuropathy in Diabetic patients type 2', EKB Journal Management System, 38(3), pp. 908-924. doi: 10.21608/bmfj.2021.21906.1200
Mahmoud, H., El-Azab, M., Butros, M., Mourad, A. The Relationship between Vitamin D level and incidence of Diabetic Peripheral Neuropathy in Diabetic patients type 2. EKB Journal Management System, 2021; 38(3): 908-924. doi: 10.21608/bmfj.2021.21906.1200

The Relationship between Vitamin D level and incidence of Diabetic Peripheral Neuropathy in Diabetic patients type 2

Benha Medical Journal
Article 171, Volume 38, Issue 3, November and December 2021, Page 908-924  XML PDF (816.82 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2021.21906.1200
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Authors
Hind Mohamed Mohamed Mahmoud email 1; Mohamed Hammad El-Azab2; Maged Kamal Fahim Butros3; AbdelNaser Ali Mourad4
1Neurology Department, Benha faculty of Medicine , Benha University, Egypt Mataria Teaching hospital Neurology resident Cairo , Egypt
2Neurology department , Benha faculty of Medicine , Benha University Benha , Egypt
3Neurology department , Benha faculty of Medicine , Benha University Cairo , Egypt
4Neurology department, Benha faculty of Medicine , Benha university Cairo , Egypt
Abstract
Abstract
Background: Vitamin D is mostly known for its essential role in the musculoskeletal system specially in Calcium and phosphorus metabolism , yet it is recently associated with different neurological disorders.
Objective: To study the relationship between vitamin D level and incidence of diabetic peripheral neuropathy in Diabetes type 2 .
Methods: A case-control study included a 100 participants , 50 type 2 diabetic patients with diabetic peripheral neuropathy and 50 healthy controls. The patients included had clinical assessment and NCS . And all patients and control had assessment of BMI ,fasting and 2-h hpp blood sugar, HbA1C, and vitamin D level.
Results: Serum vitamin D level was significantly lower in patients compared to control (P value = 0.001). For the patients group, females and patients with MNSI score more than 4 had significant lower vitamin D level (P value = 0.001 and 0.001, respectively).
Significant negative correlation was found between vitamin D level and Peroneal nerve latency ( p value 0.048 ), otherwise no correlation between vit D level and results of nerve conduction study.
Significant strong inverse correlation was found between vitamin D level and severity of PDN - MNSI score – ( p value 0.002 ) .
Conclusion: Low Vitamin D was highly prevalent in DPN patients. Females and patients with severer form of neuropathy are more liable for lower vitamin D levels
Keywords
: Diabetic peripheral neuropathy; Diabetes type2; Vitamin D; MNSI; NCS
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