LOCAL RECURRENCE OF PHYLLODES TUMORS OF THE BREAST : A META-ANALYSIS | ||||
| Ain Shams Medical Journal | ||||
| Article 6, Volume 72, Issue 2, June 2021, Page 291-299 PDF (949.62 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/asmj.2021.192520 | ||||
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| Authors | ||||
| Ismail Abd Elhakim Mohammed1; Ahmed Gamal El Dein Othman1; Mohammed Atef Mohammed Eltaib1; Ahmed Hamdy Fathy2 | ||||
| 1General Surgery Department, Faculty of Medicine, Ain Shams University, Egypt. | ||||
| 2Wady Elnatron Specialized Hospital, Egypt. | ||||
| Abstract | ||||
| Background: Phyllodes tumors (PTs) are uncommon fibroepithelial breast tumors that are capable of a diverse range of biologic behaviors. In their least aggressive form, phyllodes tumors behave like benign fibroadenomas, although with a propensity to recur locally following excision without wide margins. Aim of Work: Our study focused on local recurrence and various risk factors of phyllodes tumors of the breast through a meta-analysis. Patient and Methods: This Review involved case-control studies, case report studies, and retrospective case follow-up evaluating local recurrence (LR) rates of unilateral or bilateral phyllodes tumors. phyllodes tumors of breast and assessing various risk factors for LR. Results: Forty-eight studies compared the LR risk between Benign / malignant. There was significant higher in Malignant VS Benign regarding rate of local recurrence p-value Conclusion: The risk of LR was significantly increased from benign to borderline to malignant PTs, type of surgery, and surgical margin status may be risk factors for LR, while mitoses, tumor border, stromal cellularity, stromal atypia, stromal overgrowth, tumor necrosis had no difference regard increase risk for LR, Different management strategies could be considered for different PT grade. | ||||
| Keywords | ||||
| Phyllodes Tumors; Local Recurrence; breast tumors | ||||
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