Expression of Matrix Metalloproteinase 9 in Oreochromis Niloticus Fish and Its Active Role in Initiation and Resolution of Ammonia
Alsenosy, A., Ghoneim, H., Ibrahim, S., Aboelnour, A. (2021). Expression of Matrix Metalloproteinase 9 in Oreochromis Niloticus Fish and Its Active Role in Initiation and Resolution of Ammonia. EKB Journal Management System, 6(1), 11-16. doi: 10.21608/djvs.2020.53743.1031
Abd elwahab A. Alsenosy; Hanan Ghoneim; Safinaz Ibrahim; Asmaa Aboelnour. "Expression of Matrix Metalloproteinase 9 in Oreochromis Niloticus Fish and Its Active Role in Initiation and Resolution of Ammonia". EKB Journal Management System, 6, 1, 2021, 11-16. doi: 10.21608/djvs.2020.53743.1031
Alsenosy, A., Ghoneim, H., Ibrahim, S., Aboelnour, A. (2021). 'Expression of Matrix Metalloproteinase 9 in Oreochromis Niloticus Fish and Its Active Role in Initiation and Resolution of Ammonia', EKB Journal Management System, 6(1), pp. 11-16. doi: 10.21608/djvs.2020.53743.1031
Alsenosy, A., Ghoneim, H., Ibrahim, S., Aboelnour, A. Expression of Matrix Metalloproteinase 9 in Oreochromis Niloticus Fish and Its Active Role in Initiation and Resolution of Ammonia. EKB Journal Management System, 2021; 6(1): 11-16. doi: 10.21608/djvs.2020.53743.1031

Expression of Matrix Metalloproteinase 9 in Oreochromis Niloticus Fish and Its Active Role in Initiation and Resolution of Ammonia

Damanhour Journal of Veterinary Sciences
Article 3, Volume 6, Issue 1, August 2021, Page 11-16  XML PDF (291.43 K)
Document Type: Original Article
DOI: 10.21608/djvs.2020.53743.1031
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Authors
Abd elwahab A. Alsenosy email orcid 1; Hanan Ghoneimorcid 2; Safinaz Ibrahim3; Asmaa Aboelnour4
1Department of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt
2Department of Physiology , Faculty of Veterinary Medicine, Damanhour University, Egypt
3Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary medicine, Damanhour University, Egypt
4Department of Histology and Cytology, Faculty of Veterinary Medicine, Damanhour University, Egypt
Abstract
Dietary protein for reaching better growing Oreochromis niloticus including gradual protein levels, taking into account that optimum protein levels for grown fish will help to reduce the impact of ammonia on fish health. Herein, this study verified a theory which assumes ammonia induces changes in fish tissues responsible for ammonia excretion by a mechanism coupled to capillary endothelial cells. Fish feeding on a higher level of protein caused expression of MMP markers. Alongside, ammonia raised the activity of interstitial matrix metalloproteinases MMP-9. The rise of cell permeability maybe amended via using of an inhibitor of MMP. The results support an idea that stimulation of MMPs in brain endothelial cells contributes to the variations in permeability and cerebral vasogenic component, renal and gill tissues associated with ammonia implication. Detailed considerate of the response to ammonia stress and tolerance in tilapia can provide useful information for fish breeding professionals to expand aquaculture.
Keywords
Protein; Ammonia; MMP-9; Fish Health
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