EFFECT OF HEPARIN IN THE TREATMENT OF EXPERIMENTAL PERITONITIS | ||||
| Assiut Veterinary Medical Journal | ||||
| Article 19, Volume 6, Issue 11.12, January 1979, Page 207-216 PDF (3.02 MB) | ||||
| Document Type: Research article | ||||
| DOI: 10.21608/avmj.1979.193126 | ||||
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| Authors | ||||
| A.E. BOLBOL; A. HOSNI; M. TANTAWY; A. ABDEL-MOTTELIB | ||||
| Dept. of Surgery, Faculty of Vet. Med. Assiut University | ||||
| Abstract | ||||
| An experiment was performed to determine the effect of heparin on experimental fibrinopur ulent peritonits in dogs. Peritonitis was induced in 30 dogs by the creation of a live inches long isolated loop of terminal ileum. The mesenteric loop was not removed. The dogs were divided into a control group with no therapy, and a treatment group recei ving heparin 50 U/kg subcutaneously. Only 2 out of 15 dogs of the control group survived the observation time of 14 days; comp < /strong>ared with ll out of 15 of the heparin treated group. However, in all dogs in this experiment residual intraperitoneal sepsis was found. From this experiment, it was concluded that he parin is effective in preventing peritoneal sepsis and adhesions, as it will prevent any formation of fibrin rendering the bacteria more susceptible to cellular and non-clearing mechanisms. | ||||
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