Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients
Salem, L., Amer, A., Esawy, A. (2024). Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients. EKB Journal Management System, 30(3), 1021-1027. doi: 10.21608/zumj.2021.79462.2256
Lobna Salem; Amin Amer; Abdulla Esawy. "Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients". EKB Journal Management System, 30, 3, 2024, 1021-1027. doi: 10.21608/zumj.2021.79462.2256
Salem, L., Amer, A., Esawy, A. (2024). 'Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients', EKB Journal Management System, 30(3), pp. 1021-1027. doi: 10.21608/zumj.2021.79462.2256
Salem, L., Amer, A., Esawy, A. Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients. EKB Journal Management System, 2024; 30(3): 1021-1027. doi: 10.21608/zumj.2021.79462.2256

Efficacy of Oral Omega-3 Fatty Acids on Uremic Pruritis in Hemodialysis Patients

Zagazig University Medical Journal
Article 816, Volume 30, Issue 3, May and June 2024, Page 1021-1027  XML PDF (342.42 K)
Document Type: Original Article
DOI: 10.21608/zumj.2021.79462.2256
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Authors
Lobna Salem email 1; Amin Amer2; Abdulla Esawy3
1Department of dermatology, faculty of medicine, Zagazig university, Egypt
2Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University
3Department of of Dermatology, Venereology and Andrology, Faculty of Medicine - Zagazig University.
Abstract
Chronic kidney disease-associated pruritus (CKD-AP) is a distressing, often overlooked condition in patients with CKD and end-stage renal disease. It remains one of the most tormenting, frequent, and potentially disabling problems in patients with an advanced or end-stage renal disease who are on dialysis including peritoneal dialysis and hemodialysis. Omega-3 fatty acids are increasingly being used for their clinical benefits some of which are relevant to individuals with advanced CKD. It was found to be a safe drug that has other benefits on uremic pruritis such as reducing cholesterol, triglycerides, LDL, blood pressure, atherosclerosis, and oxidative stress.

Patient ad methods: This study was performed as a randomized, clinical trial study on 36 patients under hemodialysis three times a week, for 4 hours each session to assess the effects of Omega-3 fatty acids for treatment of pruritis in hemodialysis patients.

Conclusion: Omega-3 fatty acids was found to be a safe drug and achieved a high therapeutic response with a reasonable cost that is maintained for a relatively long period. In addition to reducing cholesterol, triglycerides, blood pressure, atherosclerosis, and oxidative stress
Keywords
pruritus; CKD; itching; Omega-3 fatty acids
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