ASSESSMENT OF CARDIAC FUNCTIONS IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS BEFORE AND AFTER TREATMENT WITH DIRECTLY ACTING ANTIVIRALS
TALKAHN, M., MAGED, K., EL KILANY, H., MOHAMED, E., MOHAMED, H., DAWOD, A. (2021). ASSESSMENT OF CARDIAC FUNCTIONS IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS BEFORE AND AFTER TREATMENT WITH DIRECTLY ACTING ANTIVIRALS. EKB Journal Management System, 51(2), 405-410. doi: 10.21608/jesp.2021.193327
MOHAMED G. TALKAHN; KHALED H. ABDEL MAGED; HESHAM H. R. EL KILANY; ESLAM S. MOHAMED; HAITHAM G. MOHAMED; AYMAN G. A. DAWOD. "ASSESSMENT OF CARDIAC FUNCTIONS IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS BEFORE AND AFTER TREATMENT WITH DIRECTLY ACTING ANTIVIRALS". EKB Journal Management System, 51, 2, 2021, 405-410. doi: 10.21608/jesp.2021.193327
TALKAHN, M., MAGED, K., EL KILANY, H., MOHAMED, E., MOHAMED, H., DAWOD, A. (2021). 'ASSESSMENT OF CARDIAC FUNCTIONS IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS BEFORE AND AFTER TREATMENT WITH DIRECTLY ACTING ANTIVIRALS', EKB Journal Management System, 51(2), pp. 405-410. doi: 10.21608/jesp.2021.193327
TALKAHN, M., MAGED, K., EL KILANY, H., MOHAMED, E., MOHAMED, H., DAWOD, A. ASSESSMENT OF CARDIAC FUNCTIONS IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS BEFORE AND AFTER TREATMENT WITH DIRECTLY ACTING ANTIVIRALS. EKB Journal Management System, 2021; 51(2): 405-410. doi: 10.21608/jesp.2021.193327

ASSESSMENT OF CARDIAC FUNCTIONS IN EGYPTIAN CHRONIC HEPATITIS C PATIENTS BEFORE AND AFTER TREATMENT WITH DIRECTLY ACTING ANTIVIRALS

Journal of the Egyptian Society of Parasitology
Article 20, Volume 51, Issue 2, August 2021, Page 405-410  XML PDF (680.33 K)
Document Type: Original Article
DOI: 10.21608/jesp.2021.193327
View on SCiNiTO View on SCiNiTO
Authors
MOHAMED G. TALKAHN1; KHALED H. ABDEL MAGED1; HESHAM H. R. EL KILANY1; ESLAM S. MOHAMED1; HAITHAM G. MOHAMED2; AYMAN G. A. DAWOD1
1Department of Internal Medicine, Hepatogastroenterology and Endoscopy
2Department of Cardiology
Abstract
Hepatitis C virus (HCV) is one of the leading causes of chronic liver disease worldwide. It
poses a serious health risk. Liver cirrhosis of is also linked to a variety of cardiovascular abnormalities.
Nowadays, direct-acting antivirals (DAAs) for hepatitis C have the potential to reduce
this disease burden, but their potential long-term cardiac effects are unknown. The aim of this
work was to see how direct-acting antivirals affect the cardiac functions of naive Egyptians
with chronic hepatitis C.
The 90 treatment-naive adult patients with chronic hepatitis C were divided into two groups
(cirrhotic and non-cirrhotic). Only two patients within the non-cirrhotic group and a patient
among cirrhotic patients showed nonspecific ST segment changes which remained unchanged
after treatments. Two non-cirrhotic patients and four cirrhotic patients showed T wave inversion,
which remained static post treatment, but without significant difference in corrected QT
interval before & after treatment between groups.
Keywords
Egypt; Patients; HCV; Liver cirrhosis; cardiac functions; Direct-acting antivirals (DAAs)
Statistics
Article View: 120
PDF Download: 174