ASSESSMENT OF CARDIAC CONTRACTILITY IN PEDIATRIC PATIENTS WITH PNEUMONIA USING ECHOCARDIOGRAPHY AND CREATINE KINASE-MB | ||||
| Al-Azhar Journal of Pediatrics | ||||
| Article 8, Volume 24, Issue 2, April 2021, Page 2083-2097 PDF (239.42 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/azjp.2021.194417 | ||||
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| Abstract | ||||
| Introduction: Community acquired pneumonia (CAP) is the most common cause of infant mortality worldwide, and one of the most common serious pediatric infectious diseases in developed countries. Recent studies documented a frequent association between CAP and the occurrence of acute cardiac complications. Aim of the work: The aim of this study is to assess myocardial affection in children hospitalized with community acquired pneumonia. Markers used are assessing blood levels of CK-MB and imaging with Echocardiography. Methods: This cross sectional case-control study. It was conducted at Al-Hussein hospital Al-Azhar University from July 2020 to February 2021, on 50 cases. 28 were males and 22 were females. Patients’ age’s ranges from 6 months to less than 5 years admitted with respiratory distress and diagnosed as community acquired pneumonia. The control group consisted of 50 matched heathy children of the same gender and age. Results: CK-MB level showed significant increase in cases compared to controls (10.8 ± 2.1 ng/ml) versus (2.7 ± 0.08 ng/ml) (P-value 0.003), Echocardiography in cases with CAP showed significant diastolic dysfunction as compared to control group. Oxygen saturation showed significant negative correlation with severity of diastolic dysfunction as demonstrated by Septal and Lateral E/e’ratio. (E = Peak early mitral inflow velocity and e’ = Tissue Doppler velocity of mitral annulus). Conclusion: The current study showed a significant statistical difference between cases and controls as regard CK-MB levels and the ability of Echocardiographic imaging for dettection of myocardial contractility affection in cases of CAP and its severity. It also points towards the ability of pulse oximetry and CK-MB to predict cardiovascular outcome in CAP cases. | ||||
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