Vitamin D and Calcium on Rheumatoid Arthritis in Egyptian Patients | ||||
Biochemistry Letters | ||||
Article 6, Volume 17, Issue 1, 2021, Page 50-58 | ||||
DOI: 10.21608/blj.2021.194510 | ||||
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Authors | ||||
Samar El-Sayed Mahmoud1; A.T. Keshta1; Abeer M. El-Shafey2 | ||||
1Biochemistry Division, Chemistry department, Faculty of Science, Zagazig University. | ||||
2Rheumatology and Rehabilitation Department, Faculty of Medicine, Zagazig University. | ||||
Abstract | ||||
Background: Rheumatoid arthritis (RA) was characterized by various systemic inflammation of joints causing damage of bone and cartilage. Aim: The current study aimed to invistigae serum level of vitamin D and calcium in RA patients compared to healthy control. Materials &Methods: This study included 90 individuals divided into two groups: Healthy volunteers group (15) and RA group (75) from Rheumatology and Rehabilitation Department, Faculty of Medicine, Zagazig university hospitals. Vitamin D and calcium levels in sera were measured as patients consumed calcium tablets. Erythrocyte sedimentation rate (ESR), C - reactive protein (CRP), Rheumatoid Factor (RF), Hemoglobin percentage (HB %) and platelet count were collected from data sheet of patient. Results: There were no significant differences between Vitamin D, calcium (slightly increased in patients) and hemoglobin in both groups. While there were a significant difference in ESR, CRP, RF, and platelet count between RA and healthy control as (p=<0.0001), (p=0.010), (p=0.015) and (p=0.03) respectively. Conclusion: Vitamin D and calcium showed non-significant difference between patients and control. | ||||
Keywords | ||||
Rheumatoid arthritis; Vitamin D; Calcium | ||||
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