Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis
Alsowey, A., Rady, S., Abdelrahman, H., Elsayed, H. (2022). Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis. EKB Journal Management System, 28(6), 1368-1376. doi: 10.21608/zumj.2021.95908.2347
Ahmed Mohamed Alsowey; Sara Mohamed Rady; HossamEldin Mansour Abdelrahman; Heba Abdelmonem Elsayed. "Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis". EKB Journal Management System, 28, 6, 2022, 1368-1376. doi: 10.21608/zumj.2021.95908.2347
Alsowey, A., Rady, S., Abdelrahman, H., Elsayed, H. (2022). 'Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis', EKB Journal Management System, 28(6), pp. 1368-1376. doi: 10.21608/zumj.2021.95908.2347
Alsowey, A., Rady, S., Abdelrahman, H., Elsayed, H. Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis. EKB Journal Management System, 2022; 28(6): 1368-1376. doi: 10.21608/zumj.2021.95908.2347

Comparison Between Gadolinium Enhanced Susceptibility Weighted Imaging And Conventional T1-Weighted Imaging In Optimizing The Recognition Of Active Plaques Of Multiple Sclerosis

Zagazig University Medical Journal
Article 23, Volume 28, Issue 6, November 2022, Page 1368-1376  XML PDF (401.37 K)
Document Type: Original Article
DOI: 10.21608/zumj.2021.95908.2347
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Authors
Ahmed Mohamed Alsowey email orcid 1; Sara Mohamed Rady2; HossamEldin Mansour Abdelrahman3; Heba Abdelmonem Elsayed4
1Radiodiagnosis Department; Faculty of medicine, Zagazig University, Egypt.
2Radiodiagnosis department, Faculty of medicine, Zagazig university, Zagazig, Egypt.
3Radiodiagnosis Department , Faculty of medicine, Zagazig University, Zagazig, Egypt.
4Radiodiagnosis Department, Faculty of medicine, Zagazig university, Zagazig Egypt.
Abstract
Background: The Gd-SWI sequence is a new important magnetic resonance imaging sequence that has been applied currently due to its ability to optimize the recognition of active plaques of MS and has a higher accurate performance than gadolinium T1WI that is currently used in clinical practice.
Aim: comparing the performance of the Gd-SWI sequence with the performance of other used sequences in clinical practice in detection of blood brain barrier (BBB) dysfunctions in MS plaques.
Methods: in this retrospective study, Twenty four patients were involved (16 females and 8males, their age ranging from 20- 42 years with the mean age 26.33 years), they were divided into two groups: 8 active cases and 22 inactive cases clinically and radiologically proven MS cases for MRI diagnosis and follow up.
Results: Two thirds of the studied group (66.7 %) had inactive lesions and one third (33.3 %) had active ones with (12.5 %) of both active and inactive lesions were progressive. There was higher ability of post-contrast SWI to demonstrate active plaques than post-contrast TIWI and there was highly statistically significance and good agreement (kappa=0.71) with 89.5% percent of agreement between post contrast enhanced lesions by SWI and T1 and statistically highly significant difference (p < 0.001).
Conclusions: Gadolinium –SWI technique improved detection accuracy of MS- contrast-enhanced plaques better than Gd-T1 SE, including their locations and morphologies.
Keywords
Keywords: Susceptibility Weighted Imaging; Multiple sclerosis; Magnetic Resonance Imaging; T1WI
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