CDPA-1 Stored Blood Induced Effect on some Haematological Parameters | ||||
| Journal of Bioscience and Applied Research | ||||
| Article 1, Volume 7, Issue 3, September 2021, Page 104-107 PDF (313.96 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jbaar.2021.195281 | ||||
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| Authors | ||||
| Nihal Abdalla Bakheit Almokhtar; Nour Mahmoud Abdelateif Ali | ||||
| Department of Hematology, Faculty of Medical Laboratory Sciences, Alneelain University, Khartoum, Sudan | ||||
| Abstract | ||||
| Background: Most blood collection bags contain 63 mL CPDA anticoagulant which is sufficient to anticoagulant and ensures the viability of blood cells in 450 mL±10% blood for up to 28–35 days when the blood is stored at 2–8°C. Prolonged storage of blood leads to alteration in cells hematologically which may lose viability with time. Aim: The study was conducted to determine the effect of storage on CPDA-1 for varying periods on some hematological parameters. Materials and methods: The study was conducted on blood donated by 30 healthy volunteer donors. Effect of storage was analyzed at 1, 7, 14, 21and 28 days intervals. Hematological parameters were measured using Mindary PS 300 hematology analyzer. Results: There is a highly significant increase in hemoglobin concentration, packed cell volume (P.C.V. %), MCV, and also a decrease in lymphocyte, granulocyte, and platelet count. The results also showed an insignificant decrease in total white blood cell count. Conclusion: There are degenerative changes observed in blood parameters in samples collected in citrate phosphate dextrose adenine (CPDA-1). | ||||
| Keywords | ||||
| CPDA-1; Hematological parameters; Storage | ||||
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