New theories in endometriosis: new knowlage may be producing novel therapies | ||||
| The Egyptian Journal of Fertility of Sterility | ||||
| Article 5, Volume 20, Issue 2, June 2016, Page 29-35 PDF (2.91 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/egyfs.2016.19532 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Laila Ezzat | ||||
| Obstetrics and gynecology department, Aswan University, Aswan, Egypt | ||||
| Abstract | ||||
| Endometriosis is a common, chronic inflammatory disease defined by the presence of extrauterine endometrial tissue. The aetiology of endometriosis is complex and multifactorial, where several not fully confirmed theories describe its pathogenesis. The current literature suggests that stem cells, dysfunctional immune response, genetic predisposition, and aberrant peritoneal environment may all be involved in the establishment and propagation of endometriotic lesions. An orchestrated scientific and clinical effort is needed to consider all factors involved in the pathogenesis of this multifaceted disease and to propose novel therapeutic targets to reach effective treatments for this distressing condition. | ||||
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